Early treatments for COVID-19
11,001 treatments have been reported as potentially beneficial for COVID-19. We currently analyze 6,409 studies for 215 treatments.
c19early.org
COVID-19 Clinical Evidence SummaryCOVID-19 Clinical Evidence
Analysis of 215 treatments and
6,400+ studies
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Naso/
oropharyngeal treatment Effective Treatment directly to the primary source of initial infection. -
Healthy lifestyles Protective Exercise, sunlight, a healthy diet, and good sleep all reduce risk.
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Immune support Effective Vitamins A, C, D, and zinc show reduced risk, as with other viruses.
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Thermotherapy Effective Methods for increasing internal body temperature, enhancing immune system function.
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Systemic agents Effective Many systemic agents reduce risk, and may be required when infection progresses.
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High-profit systemic agents Conditional Effective, but with greater access and cost barriers.
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Monoclonal antibodies Limited Utility Effective but rarely used—high cost, variant dependence, IV/SC admin.
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Acetaminophen Harmful Increased risk of severe outcomes and mortality.
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Remdesivir Harmful Increased mortality with longer followup. Increased kidney and liver injury, cardiac disorders.
We currently review studies for 215 treatments:
acebilustat acetaminophen adalimumab adintrevimab AER002 alkalinization alunacedase alfa amantadine amiodarone ammonium chloride amubarvimab andrographolide antiandrogens H1RAs antroquinonol apilimod apremilast artemisinin asapiprant aspirin astegolimab astodrimer sodium atilotrelvir atovaquone avdoralimab aviptadil azelastine azvudine baloxavir bamlan../e.. bebtelovimab belnacasan bemnifosbuvir beta-glucans BI 764198 BMS mAbs brensocatib brequinar brexanolone brilacidin bromhexine budesonide camostat cannabidiol casirivimab/i.. cenicriviroc cetylpyridinium.. chlorhexidine chlorpheniramine CK0802 clevudine colchicine conestat alfa conv. plasma crizanlizumab curcumin cyproheptadine cytokine adsorption dalcetrapib danicopan darunavir deuremidevir dexamethasone DFV890 diacerein diet dimethyl fumarate dolutegravir domperidone donidalorsen dornase alfa edaravone efmarodocokin alfa efzofitimod empagliflozin emvododstat enisamium ensifentrine ensitrelvir ensovibep epigallocatechin gallate estetrol exercise famotidine favipiravir fenretinide fluvoxamine FX06 gabapentin GB0139 gimsilumab glenzocimab goflikicept HCQ hesperidin HH-120 HuMax-IL8 hydrogen peroxide HOCl ibrutinib ibuprofen ibuzatrelvir iC1e/K indomethacin inhaled heparin interleukin-2 iota-carrageenan ivermectin ixekizumab lactoferrin lanadelumab leritrelvir levilimab lopinavir/r.. losartan losmapimod LSALT peptide lufotrelvir MAS825 masks mebendazole mefenamic acid melatonin metformin metronidazole MIB-626 molnupiravir montelukast N-acetylcysteine NaCl nafamostat naso/oropharyngeal.. niclosamide nicotine nigella sativa nitazoxanide nitric oxide obefazimod olgotrelvir olokizumab P2Et pacritinib paxlovid peg. lambda pegipanermin pemivibart pentoxifylline pHOXWELL phthalocyanine plasma-activ.. plitidepsin pomotrelvir posaconazole povidone-iodine probiotics propolis proton pump inhibitors proxalutamide quercetin ramipril ratutrelvir ravulizumab razuprotafib regdanvimab remdesivir resveratrol rhu-pGSN rNAPc2 ropeginterferon alfa-2b SA58 sargramostim sarilumab selenium selinexor sentinox siltuximab silymarin sipavibart SIR1-365 sleep SNS812 sodium bicarb.. sotrovimab spironolactone sunlight tenecteplase thermotherapy tixagevimab/c.. TMPRSS2 inhibitors tocilizumab tradipitant trimodulin TRV027 UDCA vadadustat varespladib verapamil vidofludimus calcium vilobelimab vitamin A vitamin B12 vitamin B9 vitamin C vitamin D vitamin K voxvoganan XAV-19 xiannuoxin YKYY017 zafirlukast zansecimab zavegepant zenuzolac zinc zunsemetinib
Potential benefits of 10,786
other treatments have been reported. We have not reviewed these studies.
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