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Home   COVID-19 treatment studies for Bebtelovimab  COVID-19 treatment studies for Bebtelovimab  C19 studies: Bebtelovimab  Bebtelovimab   Select treatmentSelect treatmentTreatmentsTreatments
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Outcomes in COVID-19 bebtelovimab studies
Outcomes in bebtelovimab studies. Efficacy is variant dependent. In Vitro research suggests a lack of efficacy for omicron BQ.1.1 [Planas]. Monoclonal antibody use with variants can be associated with prolonged viral loads, clinical deterioration, and immune escape [Choudhary].
0 0.5 1 1.5+ All studies 44% 2 1,134 Improvement, Studies, Patients Relative Risk Mortality 44% 2 1,134 Hospitalization 20% 2 1,134 Viral clearance 36% 1 380 RCTs -151% 1 380 Peer-reviewed 86% 1 754 Early 44% 2 1,134 Bebtelovimab for COVID-19 c19early.org/bt Dec 2022 Favorsbebtelovimab Favorscontrol
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] death 1/252 0/128 Improvement, RR [CI] Treatment Control Dryden-Peterson 86% 0.14 [0.01-2.76] death 0/377 3/377 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Early treatment 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement All studies 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement 2 bebtelovimab COVID-19 studies c19early.org/bt Dec 2022 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Effect extraction pre-specified(most serious outcome) Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] 1/252 0/128 Improvement, RR [CI] Treatment Control Dryden-Peterson 86% 0.14 [0.01-2.76] 0/377 3/377 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Early treatment 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement All studies 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement 2 bebtelovimab COVID-19 mortality results c19early.org/bt Dec 2022 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -27% 1.27 [0.25-6.46] hosp. 5/252 2/128 Improvement, RR [CI] Treatment Control Dryden-Peterson 29% 0.71 [0.32-1.59] hosp. 10/377 14/377 Tau​2 = 0.00, I​2 = 0.0%, p = 0.55 Early treatment 20% 0.80 [0.39-1.64] 15/629 16/505 20% improvement All studies 20% 0.80 [0.39-1.64] 15/629 16/505 20% improvement 2 bebtelovimab COVID-19 hospitalization results c19early.org/bt Dec 2022 Tau​2 = 0.00, I​2 = 0.0%, p = 0.55 Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] death 1/252 0/128 Improvement, RR [CI] Treatment Control Dryden-Peterson 86% 0.14 [0.01-2.76] death 0/377 3/377 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Early treatment 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement All studies 44% 0.56 [0.03-9.27] 1/629 3/505 44% improvement 2 bebtelovimab COVID-19 serious outcomes c19early.org/bt Dec 2022 Tau​2 = 1.64, I​2 = 39.9%, p = 0.7 Effect extraction pre-specified(most serious outcome) Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) 36% 0.64 [0.40-1.03] viral+ 33/252 26/128 Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.066 Early treatment 36% 0.64 [0.40-1.03] 33/252 26/128 36% improvement All studies 36% 0.64 [0.40-1.03] 33/252 26/128 36% improvement 1 bebtelovimab COVID-19 viral clearance result c19early.org/bt Dec 2022 Tau​2 = 0.00, I​2 = 0.0%, p = 0.066 Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] death 1/252 0/128 Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.58 Early treatment -151% 2.51 [0.10-61.1] 1/252 0/128 -151% improvement All studies -151% 2.51 [0.10-61.1] 1/252 0/128 -151% improvement 1 bebtelovimab COVID-19 Randomized Controlled Trials c19early.org/bt Dec 2022 Tau​2 = 0.00, I​2 = 0.0%, p = 0.58 Effect extraction pre-specified(most serious outcome) Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] 1/252 0/128 Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.58 Early treatment -151% 2.51 [0.10-61.1] 1/252 0/128 -151% improvement All studies -151% 2.51 [0.10-61.1] 1/252 0/128 -151% improvement 1 bebtelovimab COVID-19 RCT mortality result c19early.org/bt Dec 2022 Tau​2 = 0.00, I​2 = 0.0%, p = 0.58 Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Dryden-Peterson 86% 0.14 [0.01-2.76] death 0/377 3/377 Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.2 Early treatment 86% 0.14 [0.01-2.76] 0/377 3/377 86% improvement All studies 86% 0.14 [0.01-2.76] 0/377 3/377 86% improvement 1 bebtelovimab COVID-19 peer reviewed studies c19early.org/bt Dec 2022 Tau​2 = 0.00, I​2 = 0.0%, p = 0.2 Effect extraction pre-specified(most serious outcome) Favors bebtelovimab Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Lilly (RCT) -151% 2.51 [0.10-61.1] death 1/252 0/128 Improvement, RR [CI] Treatment Control Lilly (RCT) -201% 3.01 [0.12-73.2] death 1/127 0/128 Lilly (RCT) -27% 1.27 [0.25-6.46] hosp. 5/252 2/128 Lilly (RCT) -51% 1.51 [0.26-8.90] hosp. 3/127 2/128 Lilly (RCT) -2% 1.02 [0.15-7.16] hosp. 2/125 2/128 Lilly (RCT) 36% 0.64 [0.40-1.03] viral+ 33/252 26/128 Lilly (RCT) 38% 0.62 [0.35-1.10] viral+ 16/127 26/128 Lilly (RCT) 33% 0.67 [0.38-1.17] viral+ 17/125 26/128 Dryden-Peterson 86% 0.14 [0.01-2.76] death 0/377 3/377 Dryden-Peterson 43% 0.57 [0.28-1.19] death/hosp. 10/377 17/377 Dryden-Peterson 29% 0.71 [0.32-1.59] hosp. 10/377 14/377 Bebtelovimab COVID-19 outcomes c19early.org/bt Dec 2022 Favors bebtelovimab Favors control
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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