Sleep COVID-19 studies. Studies analyze sleep quality before infection, and use different definitions of sleep quality.
Recent:Wang Zhang Ahmadi Pływaczewska-Jakubowska Gao Cloosterman.
Submit updates/corrections .
Feb 1 |
(Preprint) (meta analysis) | Sleep for COVID-19: real-time meta analysis of 12 studies |
| Statistically significant improvements are seen for mortality, hospitalization, recovery, and cases. 9 studies from 9 independent teams in 4 different countries show statistically significant improvements in isolation (8 for the most se.. | ||
Oct 24 |
et al., Frontiers in Medicine, doi:10.3389/fmed.2022.1036556 | Lifestyle, course of COVID-19, and risk of Long-COVID in non-hospitalized patients |
| 17% fewer moderate/severe cases [p=0.06] and 7% lower PASC [p=0.51]. Retrospective 1,847 COVID+ patients in Poland, showing lower moderate/severe cases with improved sleep, without statistical significance. Hospitalized patients were excluded. | ||
Jul 21 |
et al., Sleep Medicine, doi:10.1016/j.sleep.2022.05.369 | Public health impact of poor sleep on COVID-19, influenza and upper respiratory infections |
| 39% lower mortality [p=0.001], 32% lower hospitalization [p<0.0001], and 7% fewer cases [p=0.04]. FinnGen Mendelian randomization study showing higher risk of COVID-19 mortality, hospitalization, and infection with insomnia. | ||
Apr 13 |
et al., medRxiv, doi:10.1101/2022.04.12.22273792 (Preprint) | Health behaviours the month prior to COVID-19 infection and the development of self-reported long COVID and specific long COVID symptoms: A longitudinal analysis of 1,811 UK adults |
| 67% improved recovery [p<0.0001]. Retrospective 1,811 COVID-19 patients in the UK, showing lower risk of self-reported long COVID with good sleep quality in the month before infection. | ||
Mar 22 2021 |
et al., BMJ Nutrition, Prevention & Health, doi:10.1136/bmjnph-2021-000228 | COVID-19 illness in relation to sleep and burnout |
| 17% fewer moderate/severe cases [p=0.03] and 11% fewer cases [p=0.003]. Retrospective 2,884 high-risk healthcare workers in France, Germany, Italy, Spain, UK, and the USA, showing shorter sleep duration associated with increased risk of COVID-19 cases and severity. | ||
Nov 30 2020 |
et al., Nature and Science of Sleep, doi:10.2147/NSS.S263488 | Reduced Sleep in the Week Prior to Diagnosis of COVID-19 is Associated with the Severity of COVID-19 |
| 81% lower severe cases [p=0.02]. Retrospective 164 COVID-19 patients and 188 controls in China, showing the risk of severe cases associated with lack of sleep. | ||
Sep 30 2021 |
et al., Infection and Drug Resistance, doi:10.2147/IDR.S331470 | Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh |
| 38% lower severe cases [p<0.0001]. Retrospective 1,500 COVID+ patients in Bangladesh, showing lower risk of severe cases with good sleep. | ||
Aug 31 2021 |
et al., Brain, Behavior, and Immunity, doi:10.1016/j.bbi.2021.04.022 | Lifestyle risk factors and infectious disease mortality, including COVID-19, among middle aged and older adults: Evidence from a community-based cohort study in the United Kingdom |
| 3% lower mortality [p=0.91]. Retrospective 468,569 adults in the UK, showing no significant difference in COVID-19 mortality based on sleep quality. | ||
Jun 18 2021 |
et al., Sleep, doi:10.1093/sleep/zsab138 | Poor sleep behavior burden and risk of COVID-19 mortality and hospitalization |
| 43% lower mortality [p=0.02] and 36% lower hospitalization [p=0.008]. UK Biobank retrospective, 46,535 participants with sleep behavior assessed between 2006 and 2010, showing higher risk of hospitalization and mortality with poor sleep. | ||
Jun 17 2021 |
et al., PLOS ONE, doi:10.1371/journal.pone.0253120 | Predictors of incident viral symptoms ascertained in the era of COVID-19 |
| 16% fewer symptomatic cases [p=0.0007]. Prospective survey based study with 14,335 participants, showing risk of viral symptoms associated with shorter sleep duration. | ||
May 14 2021 |
et al., EXCLI Journal; 20:Doc894; ISSN 1611-2156, doi:10.17179/excli2021-3451 | Association of sleep quality before and after SARS-CoV-2 infection with clinical outcomes in hospitalized patients with COVID-19 in China |
| 19% lower severe cases [p=0.0009]. Prospective study of 205 hospitalized COVID-19 patients in China, showing higher risk of severe cases with poor sleep quality. | ||
Mar 30 2021 |
et al., Thorax, doi:10.1136/thoraxjnl-2021-217487 | Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) |
| 12% fewer cases [p=0.5]. Prospective survey-based study with 15,227 people in the UK, showing reduced risk of COVID-19 cases with 8 hours sleep, with statistical significance when compared with ≥9 hours. NCT04330599. COVIDENCE UK. | ||
Dec 31 2020 |
et al., Sleep Medicine: X, doi:10.1016/j.sleepx.2020.100028 | Risk factors of SARS-CoV-2 infection in healthcare workers: a retrospective study of a nosocomial outbreak |
| 66% fewer cases [p<0.0001]. Retrospective 118 healthcare workers in China, showing higher risk of COVID-19 with poor sleep quality. | ||
Nov 5 2020 |
et al., PLOS ONE, doi:10.1371/journal.pone.0241540 | The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study |
| 36% fewer cases [p=0.04]. Case control study in China with 105 cases and 210 matched controls, showing COVID-19 cases associated with lack of sleep. | ||
Oct 21 2020 |
et al., Journal of Science and Medicine in Sport, doi:10.1016/j.jsams.2020.10.009 | Running behavior and symptoms of respiratory tract infection during the COVID-19 pandemic |
| 32% fewer symptomatic cases [p=0.09]. Analysis of 2,586 participants of a running injury prevention RCT in the Netherlands, showing higher risk of COVID-19 symptoms with sleep disturbance. | ||
Please send us corrections, updates, or comments. Vaccines and
treatments are complementary. All practical, effective, and safe means should
be used based on risk/benefit analysis. No treatment, vaccine, or intervention
is 100% available and effective for all current and future variants. We do not
provide medical advice. Before taking any medication, consult a qualified
physician who can provide personalized advice and details of risks and
benefits based on your medical history and situation. FLCCC and WCH
provide treatment protocols.
Thanks for your feedback! Please search before submitting papers and note
that studies are listed under the date they were first available, which may be
the date of an earlier preprint.