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Sleep for COVID-19
12 studies from 116 scientists
273,377 patients in 6 countries
Statistically significant improvement for mortality, hospitalization, recovery, and cases.
9 studies from 9 independent teams in 4 countries show statistically significant improvements in isolation.
COVID-19 Sleep studies. Dec 2022.
0 0.5 1 1.5+ All studies 31% Mortality 33% Hospitalization 33% Cases 14% Favorsgood sleep Favorscontrol
Sleep COVID-19 studies. Studies analyze sleep quality before infection, and use different definitions of sleep quality. Recent:
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Dec 2
Covid Analysis (Preprint) (meta analysis) Sleep for COVID-19: real-time meta analysis of 12 studies
Statistically significant improvements are seen for mortality, hospitalization, recovery, and cases. 9 studies from 9 independent teams in 4 different countries show statistically significant improvements in isolation (8 for the most se..
Oct 24
Pływaczewska-Jakubowska et al., Frontiers in Medicine, doi:10.3389/fmed.2022.1036556 Lifestyle, course of COVID-19, and risk of Long-COVID in non-hospitalized patients
17% fewer moderate/severe cases [p=0.06] and 7% lower PASC [p=0.51]. Retrospective 1,847 COVID+ patients in Poland, showing lower moderate/severe cases with improved sleep, without statistical significance. Hospitalized patients were excluded.
Jul 21
Jones et al., Sleep Medicine, doi:10.1016/j.sleep.2022.05.369 Public health impact of poor sleep on COVID-19, influenza and upper respiratory infections
39% lower mortality [p=0.001], 32% lower hospitalization [p<0.0001], and 7% fewer cases [p=0.04]. FinnGen Mendelian randomization study showing higher risk of COVID-19 mortality, hospitalization, and infection with insomnia.
Apr 13
Paul et al., medRxiv, doi:10.1101/2022.04.12.22273792 (Preprint) Health behaviours the month prior to COVID-19 infection and the development of self-reported long COVID and specific long COVID symptoms: A longitudinal analysis of 1,811 UK adults
67% improved recovery [p<0.0001]. Retrospective 1,811 COVID-19 patients in the UK, showing lower risk of self-reported long COVID with good sleep quality in the month before infection.
Mar 22
Kim et al., BMJ Nutrition, Prevention & Health, doi:10.1136/bmjnph-2021-000228 COVID-19 illness in relation to sleep and burnout
17% fewer moderate/severe cases [p=0.03] and 11% fewer cases [p=0.003]. Retrospective 2,884 high-risk healthcare workers in France, Germany, Italy, Spain, UK, and the USA, showing shorter sleep duration associated with increased risk of COVID-19 cases and severity.
Nov 30
Huang et al., Nature and Science of Sleep, doi:10.2147/NSS.S263488 Reduced Sleep in the Week Prior to Diagnosis of COVID-19 is Associated with the Severity of COVID-19
81% lower severe cases [p=0.02]. Retrospective 164 COVID-19 patients and 188 controls in China, showing the risk of severe cases associated with lack of sleep.
Sep 30
Mohsin et al., Infection and Drug Resistance, doi:10.2147/IDR.S331470 Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh
38% lower severe cases [p<0.0001]. Retrospective 1,500 COVID+ patients in Bangladesh, showing lower risk of severe cases with good sleep.
Aug 31
Ahmadi et al., Brain, Behavior, and Immunity, doi:10.1016/j.bbi.2021.04.022 Lifestyle risk factors and infectious disease mortality, including COVID-19, among middle aged and older adults: Evidence from a community-based cohort study in the United Kingdom
3% lower mortality [p=0.91]. Retrospective 468,569 adults in the UK, showing no significant difference in COVID-19 mortality based on sleep quality.
Jun 18
Li et al., Sleep, doi:10.1093/sleep/zsab138 Poor sleep behavior burden and risk of COVID-19 mortality and hospitalization
43% lower mortality [p=0.02] and 36% lower hospitalization [p=0.008]. UK Biobank retrospective, 46,535 participants with sleep behavior assessed between 2006 and 2010, showing higher risk of hospitalization and mortality with poor sleep.
Jun 17
Marcus et al., PLOS ONE, doi:10.1371/journal.pone.0253120 Predictors of incident viral symptoms ascertained in the era of COVID-19
16% fewer symptomatic cases [p=0.0007]. Prospective survey based study with 14,335 participants, showing risk of viral symptoms associated with shorter sleep duration.
May 14
Zhang et al., EXCLI Journal; 20:Doc894; ISSN 1611-2156, doi:10.17179/excli2021-3451 Association of sleep quality before and after SARS-CoV-2 infection with clinical outcomes in hospitalized patients with COVID-19 in China
19% lower severe cases [p=0.0009]. Prospective study of 205 hospitalized COVID-19 patients in China, showing higher risk of severe cases with poor sleep quality.
Mar 30
Holt et al., Thorax, doi:10.1136/thoraxjnl-2021-217487 Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
12% fewer cases [p=0.5]. Prospective survey-based study with 15,227 people in the UK, showing reduced risk of COVID-19 cases with 8 hours sleep, with statistical significance when compared with ≥9 hours. NCT04330599. COVIDENCE UK.
Dec 31
Wang et al., Sleep Medicine: X, doi:10.1016/j.sleepx.2020.100028 Risk factors of SARS-CoV-2 infection in healthcare workers: a retrospective study of a nosocomial outbreak
66% fewer cases [p<0.0001]. Retrospective 118 healthcare workers in China, showing higher risk of COVID-19 with poor sleep quality.
Nov 5
Gao et al., PLOS ONE, doi:10.1371/journal.pone.0241540 The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study
36% fewer cases [p=0.04]. Case control study in China with 105 cases and 210 matched controls, showing COVID-19 cases associated with lack of sleep.
Oct 21
Cloosterman et al., Journal of Science and Medicine in Sport, doi:10.1016/j.jsams.2020.10.009 Running behavior and symptoms of respiratory tract infection during the COVID-19 pandemic
32% fewer symptomatic cases [p=0.09]. Analysis of 2,586 participants of a running injury prevention RCT in the Netherlands, showing higher risk of COVID-19 symptoms with sleep disturbance.
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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