Global adoption of COVID-19 early treatments
Treatment |
Improvement (early) |
Studies (early) |
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| EVEnsovibep | 89% | 1 |
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| BUBudesonide | 82% | 1 |
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| MTMelatonin | 78% | 2 |
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| SPSpironolactone | 77% | 1 |
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| LFLactoferrin | 76% | 1 |
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| PXProxalutamide | 71% | 3 |
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| NSNigella Sativa | 69% | 6 |
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| BLBamlaniv../e.. | 69% | 8 |
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| COColchicine | 68% | 1 |
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| AAspirin | 67% | 1 |
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| PIPovidone-Iod.. | 65% | 14 |
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| V.AVitamin A | 62% | 3 |
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| (H)CQHydroxychlor.. | 62% | 36 |
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| IVMIvermectin | 62% | 37 |
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| BHBromhexine | 62% | 3 |
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| RDRemdesivir | 61% | 4 |
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| V.DVitamin D | 60% | 11 |
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| MFMetformin | 58% | 3 |
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| FVFluvoxamine | 56% | 6 |
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| FMFamotidine | 48% | 1 |
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| CICasirivimab/i.. | 47% | 20 |
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| AAAntiandrogen | 44% | 6 |
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| BTBebtelovimab | 44% | 2 |
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| PLPaxlovid | 44% | 22 |
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| NONitric Oxide | 42% | 2 |
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| ZnZinc | 41% | 6 |
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| PILPeg.. Lambda | 35% | 3 |
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| PBProbiotics | 34% | 4 |
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| SSotrovimab | 33% | 13 |
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| QQuercetin | 32% | 4 |
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| CCCurcumin | 30% | 11 |
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| NZNitazoxanide | 29% | 8 |
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| ENEnsitrelvir | 27% | 2 |
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| FPVFavipiravir | 26% | 17 |
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| V.CVitamin C | 24% | 5 |
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| MPMolnupiravir | 19% | 25 |
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| NACN-acetylcys.. | 3% | 3 |
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| ACEAcetaminophen | -17% | 3 |
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| TCTixagev../c.. | -29% | 2 |
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| CPConv. Plasma | -36% | 5 |
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| IBIbuprofen | -52% | 2 |
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Global adoption of early treatments. Studies, improvement, and adoption refer to early treatment only. Countries ordered by population.
Official: Unofficial:
References
Algeria
Argentina
Australia
Bahrain
Bangladesh
Belarus
Belize
Benin
Bolivia
Bosnia and Herzegovina
Botswana
Brazil
Bulgaria
Burkina Faso
Burundi
Cambodia
Cameroon
Canada
Central African Republic
Chad
Chile
China
Colombia
Congo
Costa Rica
Cuba
Czechia
DR Congo
Djibouti
Dominican Republic
Ecuador
Egypt
El Salvador
Eritrea
Ethiopia
Gabon
Germany
Ghana
Greece
Guatemala
Guinea
Guinea-Bissau
Honduras
Hungary
Iceland
India
Indonesia
Iran
Israel
Italy
Jamaica
Japan
Lebanon
Luxembourg
Madagascar
Malaysia
Mali
Mauritania
Mexico
Morocco
Namibia
New Zealand
Nicaragua
Niger
Nigeria
North Macedonia
Oman
Pakistan
Panama
Paraguay
Peru
Philippines
Poland
Portugal
Qatar
Romania
Russia
Rwanda
Saudi Arabia
Senegal
Singapore
Slovakia
South Korea
Switzerland
Thailand
Togo
Tunisia
Turkey
USA
Uganda
Ukraine
United Arab Emirates
United Kingdom
Venezuela
Vietnam
Yemen
Zimbabwe
Algeria
(Hydroxy)chloroquine -
official
- country-wide adoption
https://www.theafricareport.com/26264/coronavirus-didier-raoult-the-african-and-chloroquin..
(Internet Archive)
https://www.afrik.com/edouard-philippe-emporte-par-le-covid-didier-raoult-l-hydroxychloroq..
(Internet Archive)
https://www.theeastafrican.co.ke/news/africa/Algeria-backs-hydroxychloroquine-use/4552902-..
(Internet Archive)
https://al-bab.com/blog/2020/05/covid-19-algeria-and-morocco-continue-using-chloroquine-de..
(Internet Archive)
https://www.dovepress.com/off-label-use-of-chloroquine-and-hydroxychloroquine-for-covid-19..
(Internet Archive)
https://www.barrons.com/news/hydroxychloroquine-a-drug-dividing-the-world-01591006809
(Internet Archive)
Argentina
Ivermectin -
unofficial
- mixed usage
- Jan 26, 2021
https://www.perfil.com/noticias/agro/coronavirus-san-antonio-de-areco-implementara-tratami..
(Internet Archive)
https://www.clarin.com/sociedad/cientificos-argentinos-investigaron-ivermectina-defienden-..
(Internet Archive)
https://diario33.com.ar/misiones-profundiza-la-implementacion-de-la-ivermectina-en-pacient..
(Internet Archive)
Australia
Budesonide -
official
- country-wide adoption
Remdesivir -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Paxlovid -
official
- country-wide adoption
Sotrovimab -
official
- country-wide adoption
Molnupiravir -
official
- country-wide adoption
Acetaminophen -
official
- country-wide adoption
Ibuprofen -
official
- country-wide adoption
Bahrain
(Hydroxy)chloroquine -
official
- country-wide adoption
https://english.alarabiya.net/en/News/gulf/2020/03/26/Bahrain-one-of-the-first-countries-t..
(Internet Archive)
https://www.gulf-insider.com/coronavirus-bahrains-therapeutic-medication-proved-effective/
(Internet Archive)
Bangladesh
Ivermectin -
official
- country-wide adoption
Belarus
(Hydroxy)chloroquine -
unofficial
- mixed usage
Belize
Ivermectin -
official
- country-wide adoption
- used for serious cases
- Dec 18, 2020
Benin
(Hydroxy)chloroquine -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Bolivia
Ivermectin -
official
- country-wide adoption
Bosnia and Herzegovina
Proxalutamide -
official
- used in some regions
Botswana
Ivermectin -
unofficial
- mixed usage
Brazil
Ivermectin -
unofficial
- used in some regions
- Jan 26, 2021
https://terrabrasilnoticias.com/2021/01/associacao-medica-do-rn-defende-tratamento-precoce..
(Internet Archive)
Bulgaria
Ivermectin -
official
- country-wide adoption
Burkina Faso
(Hydroxy)chloroquine -
official
- country-wide adoption
https://www.francetvinfo.fr/monde/afrique/senegal/ces-pays-africains-qui-ont-decide-de-con..
(Internet Archive)
Burundi
(Hydroxy)chloroquine -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Zinc -
official
- country-wide adoption
Cambodia
Ivermectin -
official
- country-wide adoption
Cameroon
(Hydroxy)chloroquine -
official
- country-wide adoption
https://www.france24.com/en/20200503-covid-19-in-cameroon-a-chloroquine-therapy-hailed-by-..
(Internet Archive)
https://www.voanews.com/science-health/coronavirus-outbreak/cameroon-begins-large-scale-ch..
(Internet Archive)
Casirivimab/imdevimab -
official
- country-wide adoption
Canada
Budesonide -
official
- isolated use
Bamlanivimab/etesevimab -
official
- country-wide adoption
Fluvoxamine -
official
- isolated use
Casirivimab/imdevimab -
official
- country-wide adoption
Paxlovid -
official
- country-wide adoption
Sotrovimab -
official
- country-wide adoption
Central African Republic
(Hydroxy)chloroquine -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Chad
(Hydroxy)chloroquine -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Chile
(Hydroxy)chloroquine -
unofficial
- mixed usage
China
Aspirin -
official
- country-wide adoption
(Hydroxy)chloroquine -
official
- country-wide adoption
- CQ is used instead of HCQ
https://www.archyde.com/china-approves-chloroquine-instead-of-hydroxychloroquine-against-c..
(Internet Archive)
Bromhexine -
official
- country-wide adoption
Paxlovid -
official
- country-wide adoption
Probiotics -
official
- country-wide adoption
Molnupiravir -
official
- country-wide adoption
N-acetylcysteine -
official
- country-wide adoption
Acetaminophen -
official
- country-wide adoption
Convalescent Plasma -
official
- country-wide adoption
Ibuprofen -
official
- country-wide adoption
Colombia
Ivermectin -
unofficial
- used in many regions
Congo
(Hydroxy)chloroquine -
official
- country-wide adoption
Remdesivir -
official
- country-wide adoption
Costa Rica
(Hydroxy)chloroquine -
official
- country-wide adoption
https://ticotimes.net/2020/06/15/news-briefs-reopening-plans-on-track-hydroxychloroquine-u..
(Internet Archive)
Cuba
(Hydroxy)chloroquine -
official
- country-wide adoption
Czechia
(Hydroxy)chloroquine -
official
- country-wide adoption
https://news.expats.cz/weekly-czech-news/czech-health-ministry-permits-temporary-use-of-hy..
(Internet Archive)
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Ivermectin -
official
- isolated use
- authorized, but reportedly almost no use
https://www.idnes.cz/zpravy/domaci/invermektin-v-cesku-konci-ministerstvo-mu-neda-dalsi-vy..
(Internet Archive)
https://www.novinky.cz/domaci/clanek/ivermektin-bude-moci-jit-do-vsech-lekaren-40353842
(Internet Archive)
https://www.sukl.cz/leciva/informace-o-povoleni-pouzivani-neregistrovaneho-leciveho-5
(Internet Archive)
https://www.mzcr.cz/rozhodnuti-o-docasnem-povoleni-distribuce-vydeje-a-pouzivani-neregistr..
(Internet Archive)
https://www.mzcr.cz/wp-content/uploads/2021/03/Rozhodnut%C3%AD-o-do%C4%8Dasn%C3%A9m-povole..
(Internet Archive)
DR Congo
(Hydroxy)chloroquine -
official
- country-wide adoption
Djibouti
(Hydroxy)chloroquine -
official
- country-wide adoption
https://www.dovepress.com/off-label-use-of-chloroquine-and-hydroxychloroquine-for-covid-19..
(Internet Archive)
Dominican Republic
Ivermectin -
official
- country-wide adoption
- Sep 30, 2020
Ecuador
(Hydroxy)chloroquine -
unofficial
- mixed usage
Ivermectin -
unofficial
- mixed usage
Egypt
Lactoferrin -
official
- country-wide adoption
(Hydroxy)chloroquine -
official
- country-wide adoption
- Nov 30, 2020
https://www.researchgate.net/publication/345813633_Management_Protocol_for_COVID-19_Patien..
(Internet Archive)
https://www.dovepress.com/off-label-use-of-chloroquine-and-hydroxychloroquine-for-covid-19..
(Internet Archive)
https://www.beegsonews.com/egypt-reveals-results-of-hydroxychloroquine-with-people-with-co..
(Internet Archive)
https://www.egypttoday.com/Article/1/83104/Egypt-uses-chloroquine-in-treating-COVID-19-pat..
(Internet Archive)
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
https://wwww.dailynewssegypt.com/2020/05/30/egypt-still-uses-hcq-for-treating-some-covid-1..
(Internet Archive)
Ivermectin -
official
- country-wide adoption
- Nov 30, 2020
Remdesivir -
official
- country-wide adoption
- Nov 30, 2020
Zinc -
official
- country-wide adoption
- Nov 30, 2020
Favipiravir -
official
- country-wide adoption
- Nov 30, 2020
Vitamin C -
official
- country-wide adoption
- Nov 30, 2020
El Salvador
(Hydroxy)chloroquine -
unofficial
- mixed usage
Ivermectin -
official
- country-wide adoption
Eritrea
(Hydroxy)chloroquine -
official
- country-wide adoption
Ethiopia
(Hydroxy)chloroquine -
official
- country-wide adoption
Gabon
(Hydroxy)chloroquine -
official
- country-wide adoption
Germany
Budesonide -
unofficial
- used in some regions
(Hydroxy)chloroquine -
unofficial
- mixed usage
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
https://blogs.mediapart.fr/brigitte-pascall/blog/211020/lallemagne-massivement-utilise-lhy..
(Internet Archive)
https://www.spiegel.de/wirtschaft/covid-19-deutsche-aerzte-verschrieben-von-donald-trump-e..
(Internet Archive)
https://rp-online.de/wirtschaft/unternehmen/corona-krise-bayer-spendet-acht-millionen-chlo..
(Internet Archive)
https://www.deutsche-apotheker-zeitung.de/news/artikel/2020/04/06/bfarm-keine-ambulanten-o..
(Internet Archive)
Ivermectin -
unofficial
- isolated use
- Dec 31, 2020
https://www.barmherzige-muenchen.de/medien/meldungen/artikel/global-partner-flccc-alliance..
(Internet Archive)
Fluvoxamine -
unofficial
- used in some regions
Ghana
Proxalutamide -
official
- country-wide adoption
(Hydroxy)chloroquine -
official
- country-wide adoption
https://www.dovepress.com/off-label-use-of-chloroquine-and-hydroxychloroquine-for-covid-19..
(Internet Archive)
Remdesivir -
official
- country-wide adoption
Greece
(Hydroxy)chloroquine -
official
- country-wide adoption
https://medicalxpress.com/news/2020-06-global-controversy-greece-chloroquine.html
(Internet Archive)
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
Guatemala
Ivermectin -
official
- country-wide adoption
- Jan 23, 2021
Guinea
(Hydroxy)chloroquine -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Guinea-Bissau
(Hydroxy)chloroquine -
official
- country-wide adoption
Honduras
Colchicine -
official
- country-wide adoption
(Hydroxy)chloroquine -
official
- country-wide adoption
Ivermectin -
official
- country-wide adoption
- Apr 23, 2020
https://www.prnewswire.com/news-releases/honduras-treatment-for-covid-19-stands-out-worldw..
(Internet Archive)
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00024-9/fulltext
(Internet Archive)
Fluvoxamine -
official
- mixed usage
Zinc -
official
- country-wide adoption
Hungary
Bamlanivimab/etesevimab -
official
- country-wide adoption
Casirivimab/imdevimab -
official
- country-wide adoption
Sotrovimab -
official
- country-wide adoption
Favipiravir -
official
- country-wide adoption
Molnupiravir -
official
- country-wide adoption
Iceland
(Hydroxy)chloroquine -
unofficial
- mixed usage
https://grapevine.is/news/2020/03/31/iceland-expects-huge-shipment-of-anti-malarial-drug-t..
(Internet Archive)
India
Budesonide -
official
- country-wide adoption
(Hydroxy)chloroquine -
unofficial
- mixed usage
https://www.icmr.gov.in/pdf/covid/techdoc/COVID19_Management_Algorithm_22042021_v1.pdf
(Internet Archive)
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30313-3/fulltext
(Internet Archive)
https://indianexpress.com/article/cities/pune/maharashtra-expands-use-of-hydroxychloroquin..
(Internet Archive)
https://web.archive.org/web/20210412200113/https://www.hsj.gr/medicine/is-there-a-correlat..
https://www.oneindia.com/india/no-covid-19-death-in-manipur-mizoram-nagaland-sikkim-so-far..
(Internet Archive)
https://www.msn.com/en-ph/news/world/india-backs-hydroxychloroquine-for-virus-prevention/a..
(Internet Archive)
https://indianexpress.com/article/india/vadodara-administration-drive-hcq-helping-in-conta..
(Internet Archive)
Ivermectin -
unofficial
- used in many regions
https://trialsitenews.com/icmr-includes-ivermectin-for-covid-19-indication-in-national-lis..
(Internet Archive)
https://zeenews.india.com/india/covid-19-uttarakhand-government-to-distribute-ivermectin-t..
(Internet Archive)
https://transformingindia.mygov.in/covid19/guidelines-for-home-isolation-of-mild-asymptoma..
(Internet Archive)
https://www.mohfw.gov.in/pdf/RevisedguidelinesforHomeIsolationofmildasymptomaticCOVID19cas..
(Internet Archive)
https://www.icmr.gov.in/pdf/covid/techdoc/COVID19_Management_Algorithm_22042021_v1.pdf
(Internet Archive)
https://transformingindia.mygov.in/wp-content/uploads/2021/04/Guidelines-for-Home-Isolatio..
(Internet Archive)
https://www.panchayat.gov.in/documents/20126/0/MoPR-Advisory+on+SoPs+on+COVID-19+Containme..
(Internet Archive)
https://transformingindia.mygov.in/covid19/clinical-guidance-for-management-of-adult-covid..
(Internet Archive)
https://www.deshgujarat.com/2021/04/22/live-ivermectin-and-fevipiravir-added-to-clinical-p..
(Internet Archive)
https://web.archive.org/web/20201004145236/http://dgmhup.gov.in/DocumentsCovid19/1621.pdf
https://www.wbhealth.gov.in/uploaded_files/corona/WB_Covid_protocol_book_25.09_.20_(1)_.pd..
(Internet Archive)
https://trialsitenews.com/an-unlikely-nation-is-kicking-this-pandemic-guess-which-then-why..
(Internet Archive)
Remdesivir -
official
- isolated use
Nitric Oxide -
official
- country-wide adoption