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All TRV027 studies
 
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c19early.org COVID-19 treatment researchTRV027TRV027 (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

Outcomes in COVID-19 TRV027 studies

0 0.5 1 1.5+ All studies -54% 2 318 Improvement, Studies, Patients Relative Risk Mortality -54% 2 318 RCTs -54% 2 318 RCT mortality -54% 2 318 Late -54% 2 318 TRV027 for COVID-19 c19early.org November 2024 FavorsTRV027 Favorscontrol
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] death 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] death 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 studies c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Effect extraction pre-specified(most serious outcome) Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 mortality results c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] death 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] death 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 serious outcomes c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Effect extraction pre-specified(most serious outcome) Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ ACTIV-4 Self (DB RCT) -35% 1.35 [0.89-2.08] no recov. 145 (n) 145 (n) Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.17 Late treatment -35% 1.35 [0.89-2.08] 145 (n) 145 (n) 35% higher risk All studies -35% 1.35 [0.89-2.08] 145 (n) 145 (n) 35% higher risk 1 TRV027 COVID-19 recovery result c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.17 Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] death 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] death 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 Randomized Controlled Trials c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Effect extraction pre-specified(most serious outcome) Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 RCT mortality results c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] death 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] death 145 (n) 145 (n) Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Late treatment -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk All studies -54% 1.54 [0.78-3.02] 2/160 1/158 54% higher risk 2 TRV027 COVID-19 peer reviewed studies c19early.org November 2024 Tau​2 = 0.00, I​2 = 0.0%, p = 0.21 Effect extraction pre-specified(most serious outcome) Favors TRV027 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ COVRAS Robbins (DB RCT) -73% 1.73 [0.18-17.0] death 2/15 1/13 Improvement, RR [CI] Treatment Control ACTIV-4 Self (DB RCT) -52% 1.52 [0.75-3.08] death 145 (n) 145 (n) ACTIV-4 Self (DB RCT) -35% 1.35 [0.89-2.08] no recov. 145 (n) 145 (n) TRV027 COVID-19 outcomes c19early.org November 2024 Favors TRV027 Favors control
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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