Tradipitant: meta-analysis of COVID-19 studies

All studies Mortality Serious outcomes RCTs RCT mortality All outcomes

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−36%

Mortality (1)−36%

RCTs (1)−36%

Late (1)−36%

00.511.5+

← Tradipitant
reduces riskIncreased
risk →

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c19early.org

October 2026

Tradipitant COVID-19 studies

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.61death16/6913/76ODYSSEY

Late treatment−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.37

All studies−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.3700.511.52+

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← Tradipitant
reduces riskTradipitant
increases risk →

c19early.org

October 2026

Tradipitant COVID-19 mortality results

StudyImprovementRR · 95% CITreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.6116/6913/76ODYSSEY

Late treatment−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.37

All studies−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.3700.511.52+

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← Tradipitant
reduces riskTradipitant
increases risk →

c19early.org

October 2026

Tradipitant COVID-19 serious outcomes

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.61death16/6913/76ODYSSEY

Late treatment−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.37

All studies−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.3700.511.52+

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← Tradipitant
reduces riskTradipitant
increases risk →

c19early.org

October 2026

Tradipitant COVID-19 Randomized Controlled Trials

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.61death16/6913/76ODYSSEY

Late treatment−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.37

All studies−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.3700.511.52+

Rotate screen for more detailsIncrease width for more details

← Tradipitant
reduces riskTradipitant
increases risk →

c19early.org

October 2026

Tradipitant COVID-19 RCT mortality results

StudyImprovementRR · 95% CITreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.6116/6913/76ODYSSEY

Late treatment−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.37

All studies−36%1.36 · 0.70–2.6116/6913/7636% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.3700.511.52+

Rotate screen for more detailsIncrease width for more details

← Tradipitant
reduces riskTradipitant
increases risk →

c19early.org

October 2026

Tradipitant COVID-19 outcomes

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Polymer.. (DB RCT)−36%1.36 · 0.70–2.61death16/6913/76ODYSSEY

00.511.52+

Rotate screen for more detailsIncrease width for more details

← Tradipitant
reduces riskTradipitant
increases risk →