$0 $1,000 $2,000+ -25+% 0% 25% 50% Treatment cost (US$) Efficacy vs. cost for COVID-19 treatments +59 more high-profit drugs PPIs -46% BMS mAbs -36% >$2,000 Darunavir -34% Acetaminophen -28% Cenicriviroc -28% >$2,000 Cannabidiol Lufotrelvir >$2,000 Losartan Sargramostim >$2,000 Dexamethasone Lopinavir/ritonavir Ravulizumab >$2,000 Remdesivir $3,120 Conv. Plasma $5,000 Sarilumab >$2,000 Ibuprofen Masks Molnupiravir mutagenic/teratogenic Aspirin Tocilizumab Favipiravir Paxlovid Ratutrelvir Famotidine Vitamin C Sotrovimab $2,100 Colchicine TMPRSS2 i.. NAC Amubarvimab/r.. Vilobelimab $6,350 Ensitrelvir Azvudine Budesonide Probiotics HCQ Tixagevimab/c.. Zinc Antiandro.. Sleep Metformin Vitamin A Melatonin Bebtelovimab Nitric Oxide Quercetin H1RAs CPC Vitamin D H. Peroxide Exercise Fluvox. Sunlight Curcumin N. Sativa NaHCO₃ Casirivimab/i.. $2,100 Bamlanivimab/e.. Ensovibep >$2,000 PVP-I pH+ Diet Regdanvimab $2,100 Thermotherapy Ivermectin Lifestyle / free No prescription Prescription required High-cost Lowerrisk Higherrisk c19early.org July 2026 USA official early treatments COVID-19 involves the interplay of 500+ host/viral proteins/factors, modulated by many treatments. 0.5% of 11,000+proposed treatments show efficacy with ≥3 studies.Protocols combine treatments, none are 100% effective.c19early analyzes over 6,600 studies for 225 treatments.
GB-0669 is a half-life-extended, AI-designed monoclonal antibody targeting the conserved SARS-CoV-2 spike S2 stem helix, administered as a single intravenous infusion. Recent:
Borriello.
Jul 14
Borriello et al., The Journal of Infectious Diseases, doi:10.1093/infdis/jiag349 Randomized, Double-Blind, Placebo-Controlled First-in-Human Trial of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix
Phase 1 double-blind, placebo-controlled RCT of 51 healthy volunteers showing that GB-0669 - an AI-designed, half-life-extended monoclonal antibody targeting the conserved SARS-CoV-2 spike S2 stem helix - was well-tolerated, with no dose-..