Domperidone: meta-analysis of COVID-19 studies

All studies Recovery Viral clearance RCTs Peer-reviewed All outcomes

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−36%

Viral clearance (1)−15%

RCTs (1)−36%

Early (1)−36%

00.511.5+

← Domperidone
reduces riskIncreased
risk →

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c19early.org

October 2026

Domperidone COVID-19 studies

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Rabanal .. (DB RCT)−36%1.36 · 0.83–2.23no recov.87 (n)86 (n)

Early treatment−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

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← Domperidone
reduces riskDomperidone
increases risk →

c19early.org

October 2026

Domperidone COVID-19 recovery results

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Rabanal .. (DB RCT)−36%1.36 · 0.83–2.23no recov.87 (n)86 (n)

Early treatment−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

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← Domperidone
reduces riskDomperidone
increases risk →

c19early.org

October 2026

Domperidone COVID-19 viral clearance results

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Rabanal .. (DB RCT)−15%1.15 · 0.73–1.82viral+28/8724/86

Early treatment−15%1.15 · 0.73–1.8228/8724/8615% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.55

All studies−15%1.15 · 0.73–1.8228/8724/8615% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.5500.511.52+

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← Domperidone
reduces riskDomperidone
increases risk →

c19early.org

October 2026

Domperidone COVID-19 Randomized Controlled Trials

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Rabanal .. (DB RCT)−36%1.36 · 0.83–2.23no recov.87 (n)86 (n)

Early treatment−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

Rotate screen for more detailsIncrease width for more details

← Domperidone
reduces riskDomperidone
increases risk →

c19early.org

October 2026

Domperidone COVID-19 peer reviewed studies

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Rabanal .. (DB RCT)−36%1.36 · 0.83–2.23no recov.87 (n)86 (n)

Early treatment−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−36%1.36 · 0.83–2.2387 (n)86 (n)36% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

Rotate screen for more detailsIncrease width for more details

← Domperidone
reduces riskDomperidone
increases risk →

c19early.org

October 2026

Domperidone COVID-19 outcomes

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

00.511.52+

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← Domperidone
reduces riskDomperidone
increases risk →