Gabapentin: meta-analysis of COVID-19 studies

All studies Hospitalization Recovery RCTs Peer-reviewed All outcomes

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−11%

Hospitalization (1)−11%

RCTs (1)−11%

Late (1)−11%

00.511.5+

← Gabapentin
reduces riskIncreased
risk →

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c19early.org

October 2026

Gabapentin COVID-19 studies

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−11%1.11 · 0.94–1.32hosp. time76 (n)53 (n)OT¹

Late treatment−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

¹ OT: comparison with other treatment

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← Gabapentin
reduces riskGabapentin
increases risk →

c19early.org

October 2026

Gabapentin COVID-19 hospitalization results

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−11%1.11 · 0.94–1.32hosp. time76 (n)53 (n)OT¹

Late treatment−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

¹ OT: comparison with other treatment

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← Gabapentin
reduces riskGabapentin
increases risk →

c19early.org

October 2026

Gabapentin COVID-19 recovery results

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−97%1.97 · 1.61–2.40no recov.76 (n)53 (n)OT¹

Late treatment−97%1.97 · 1.61–2.4076 (n)53 (n)97% higher risk

Tau² = 0.00, I² = 0.0%, p < 0.0001

All studies−97%1.97 · 1.61–2.4076 (n)53 (n)97% higher risk

Tau² = 0.00, I² = 0.0%, p < 0.000100.511.52+

¹ OT: comparison with other treatment

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← Gabapentin
reduces riskGabapentin
increases risk →

c19early.org

October 2026

Gabapentin COVID-19 Randomized Controlled Trials

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−11%1.11 · 0.94–1.32hosp. time76 (n)53 (n)OT¹

Late treatment−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

¹ OT: comparison with other treatment

Rotate screen for more detailsIncrease width for more details

← Gabapentin
reduces riskGabapentin
increases risk →

c19early.org

October 2026

Gabapentin COVID-19 peer reviewed studies

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−11%1.11 · 0.94–1.32hosp. time76 (n)53 (n)OT¹

Late treatment−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.23

All studies−11%1.11 · 0.94–1.3276 (n)53 (n)11% higher risk

Tau² = 0.00, I² = 0.0%, p = 0.2300.511.52+

¹ OT: comparison with other treatment

Rotate screen for more detailsIncrease width for more details

← Gabapentin
reduces riskGabapentin
increases risk →

c19early.org

October 2026

Gabapentin COVID-19 outcomes

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Soltani (RCT)−11%1.11 · 0.94–1.32hosp. time76 (n)53 (n)OT¹ Soltani (RCT)−97%1.97 · 1.61–2.40no recov.76 (n)53 (n)OT¹ Soltani (RCT)−66%1.66 · 1.36–2.02no recov.76 (n)53 (n)OT¹

00.511.52+

¹ OT: comparison with other treatment

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← Gabapentin
reduces riskGabapentin
increases risk →