Outcomes in COVID-19 SNS812 studies

0 0.5 1 1.5+ All studies 17% 1 90 Improvement, Studies, Patients Relative Risk Viral clearance 17% 1 90 RCTs 17% 1 90 Early 17% 1 90 SNS812 for COVID-19 c19early.org November 2025 FavorsSNS812 Favorscontrol
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Chang (DB RCT) 17% 0.83 [0.71-0.96] viral load 45 (n) 45 (n) Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Early treatment 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk All studies 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk 1 SNS812 COVID-19 study c19early.org November 2025 Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Effect extraction pre-specified(most serious outcome) Favors SNS812 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Chang (DB RCT) 17% 0.83 [0.71-0.96] viral load 45 (n) 45 (n) Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Early treatment 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk All studies 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk 1 SNS812 COVID-19 viral clearance result c19early.org November 2025 Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Favors SNS812 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Chang (DB RCT) 17% 0.83 [0.71-0.96] viral load 45 (n) 45 (n) Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Early treatment 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk All studies 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk 1 SNS812 COVID-19 Randomized Controlled Trial c19early.org November 2025 Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Effect extraction pre-specified(most serious outcome) Favors SNS812 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Chang (DB RCT) 17% 0.83 [0.71-0.96] viral load 45 (n) 45 (n) Improvement, RR [CI] Treatment Control Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Early treatment 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk All studies 17% 0.83 [0.71-0.96] 45 (n) 45 (n) 17% lower risk 1 SNS812 COVID-19 peer reviewed studies c19early.org November 2025 Tau​2 = 0.00, I​2 = 0.0%, p = 0.015 Effect extraction pre-specified(most serious outcome) Favors SNS812 Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Chang (DB RCT) 17% 0.83 [0.71-0.96] viral load 45 (n) 45 (n) Improvement, RR [CI] Treatment Control Chang (DB RCT) 13% 0.87 [0.72-1.04] viral load 44 (n) 45 (n) Chang (DB RCT) 19% 0.81 [0.69-0.94] viral time 45 (n) 45 (n) SNS812 COVID-19 outcomes c19early.org November 2025 Favors SNS812 Favors control