Outcomes in COVID-19 PPE studies
Outcomes in PPE studies. Only RCTs are included.
0
0.5
1
1.5+
All studies
2%
4
351,091
Improvement, Studies, Patients
Relative Risk
Cases
2%
4
351,091
RCTs
2%
4
351,091
Prophylaxis
2%
4
351,091
PPE for COVID-19
c19 early .org
March 2025
Favors PPE
Favors control
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
DANMASK-19
Bundgaard (RCT)
18%
0.82 [0.54-1.23]
cases
42/2,392
53/2,470
Improvement, RR [CI]
Treatment
Control
Abaluck (RCT)
9%
0.91 [0.81-0.99]
symp. case
178,322 (n)
163,861 (n)
TRACE/STOPCOV
Smith (SB RCT)
-98%
1.98 [0.97-4.03]
cases
137 (n)
108 (n)
Solberg (RCT)
-7%
1.07 [0.58-1.96]
cases
21/1,834
21/1,967
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Prophylaxis
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
All studies
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
4 PPE COVID-19 studies
c19 early .org
March 2025
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Effect extraction pre-specified (most serious outcome)
Favors PPE
Favors control
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
DANMASK-19
Bundgaard (RCT)
18%
0.82 [0.54-1.23]
cases
42/2,392
53/2,470
Improvement, RR [CI]
Treatment
Control
Abaluck (RCT)
9%
0.91 [0.81-0.99]
symp. case
178,322 (n)
163,861 (n)
TRACE/STOPCOV
Smith (SB RCT)
-98%
1.98 [0.97-4.03]
cases
137 (n)
108 (n)
Solberg (RCT)
-7%
1.07 [0.58-1.96]
cases
21/1,834
21/1,967
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Prophylaxis
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
All studies
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
4 PPE COVID-19 case results
c19 early .org
March 2025
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Favors PPE
Favors control
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
DANMASK-19
Bundgaard (RCT)
18%
0.82 [0.54-1.23]
cases
42/2,392
53/2,470
Improvement, RR [CI]
Treatment
Control
Abaluck (RCT)
9%
0.91 [0.81-0.99]
symp. case
178,322 (n)
163,861 (n)
TRACE/STOPCOV
Smith (SB RCT)
-98%
1.98 [0.97-4.03]
cases
137 (n)
108 (n)
Solberg (RCT)
-7%
1.07 [0.58-1.96]
cases
21/1,834
21/1,967
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Prophylaxis
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
All studies
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
4 PPE COVID-19 Randomized Controlled Trials
c19 early .org
March 2025
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Effect extraction pre-specified (most serious outcome)
Favors PPE
Favors control
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
DANMASK-19
Bundgaard (RCT)
18%
0.82 [0.54-1.23]
cases
42/2,392
53/2,470
Improvement, RR [CI]
Treatment
Control
Abaluck (RCT)
9%
0.91 [0.81-0.99]
symp. case
178,322 (n)
163,861 (n)
TRACE/STOPCOV
Smith (SB RCT)
-98%
1.98 [0.97-4.03]
cases
137 (n)
108 (n)
Solberg (RCT)
-7%
1.07 [0.58-1.96]
cases
21/1,834
21/1,967
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Prophylaxis
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
All studies
2%
0.98 [0.76-1.25]
63/182,685
74/168,406
2% lower risk
4 PPE COVID-19 peer reviewed studies
c19 early .org
March 2025
Tau2 = 0.03, I2 = 41.5%, p = 0.87
Effect extraction pre-specified (most serious outcome)
Favors PPE
Favors control
0
0.25
0.5
0.75
1
1.25
1.5
1.75
2+
DANMASK-19
Bundgaard (RCT)
18%
0.82 [0.54-1.23]
cases
42/2,392
53/2,470
Improvement, RR [CI]
Treatment
Control
Abaluck (RCT)
9%
0.91 [0.81-0.99]
symp. case
178,322 (n)
163,861 (n)
TRACE/STOPCOV
Smith (SB RCT)
-98%
1.98 [0.97-4.03]
cases
137 (n)
108 (n)
TRACE/STOPCOV
Smith (SB RCT)
-58%
1.58 [0.29-8.45]
cases
4/137
2/108
TRACE/STOPCOV
Smith (SB RCT)
-164%
2.64 [0.89-7.80]
misc.
137 (n)
108 (n)
TRACE/STOPCOV
Smith (SB RCT)
-373%
4.73 [0.58-38.7]
misc.
6/137
1/108
TRACE/STOPCOV
Smith (SB RCT)
-176%
2.76 [0.58-13.0]
misc.
7/137
2/108
TRACE/STOPCOV
Smith (SB RCT)
-358%
4.58 [0.22-94.3]
misc.
2/137
0/108
TRACE/STOPCOV
Smith (SB RCT)
69%
0.31 [0.01-7.44]
misc.
0/137
1/108
Solberg (RCT)
-7%
1.07 [0.58-1.96]
cases
21/1,834
21/1,967
PPE COVID-19 outcomes
c19 early .org
March 2025
Favors PPE
Favors control
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