Pomotrelvir for COVID-19
1 study with 230 patients
No significant improvements are seen in meta analysis to date.
COVID-19 Pomotrelvir studies. Dec 2025. c19early.org
0 0.5 1 1.5+ All studies -1% Viral clearance -39% RCTs -1% Early -1% Favorspomotrelvir Favorscontrol
Feb 6
2024
Borroto-Esoda et al., Microbiology Spectrum, doi:10.1128/spectrum.02980-23 SARS-CoV-2 viral dynamics in a placebo-controlled phase 2 study of patients infected with the SARS-CoV-2 Omicron variant and treated with pomotrelvir
1% worse recovery (p=1) and 252% worse results (p=0.1). RCT 242 symptomatic outpatients showing no significant difference in viral clearance or symptom resolution with pomotrelvir treatment initiated within 5 days of symptom onset. Based on the description provided it is not clear why the numb..