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c19early.org COVID-19 treatment researchPemivibartPemivibart (more..)
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$0 $1,000 $2,000+ -25+% 0% 25% 50% Treatment cost (US$) Efficacy vs. cost for COVID-19 treatments Glenzocimab -60% ~$2,000+ BMS mAbs -36% ~$2,000+ Acetaminophen -28% Lufotrelvir ~$2,000+ Cannabidiol Losartan Vitamin B9 Conv. Plasma $5,000 Acebilustat ~$2,000+ Ibuprofen Remdesivir $3,120 Ambavirumab/r.. Aspirin Molnupiravir mutagenic/teratogenic Favipiravir Famotidine Paxlovid Vitamin C NAC Sotrovimab $2,100 Nitric Oxide Colchicine HCQ Zinc Budesonide Probiotics Metformin Azvudine Sleep Antiandro.. Bebtelovimab Vitamin A Vitamin D Sunlight H. Peroxide Fluvox. Exercise Curcumin Tixagevimab/c.. N. Sativa NaHCO₃ Melatonin Ensovibep ~$2,000+ Bamlanivimab/e.. Casirivimab/i.. $2,100 pH+ Quercetin Diet PVP-I Thermotherapy Ivermectin Regdanvimab $2,100 Lifestyle / free No prescription Prescription required High-cost Lower risk Higher risk c19early.org June 2024 COVID-19 involves the interplay of 50+ host/viral proteins andfactors, known to be modulated by many treatments. 0.6% of7,000+ proposed treatments show efficacy with ≥3 studies.Protocols combine treatments, none are 100% effective.c19early analyzes over 4,300 studies for 77 treatments.
Home   Post   Share   @CovidAnalysis   OutcomesOutcomes   mAb use may create new variants that spread globally Focosi, Leducq, and may be associated with prolonged viral loads, clinical deterioration, and immune escape Choudhary, Günther, Leducq. Recent:
Mahoney
Invivyd.
Submit updates/corrections. Summary.
Mar 22
Invivyd Press Release Invivyd announces FDA authorization for emergency use of Pemgarda™ (formerly VYD222) for pre-exposure prophylaxis (PrEP) of COVID-19
RCT 623 patients reporting immunobridging results from cohort A with 306 immunocompromised patients. Immunobridging estimates efficacy from the relationship between serum virus neutralizing antibody titers and clinical efficacy demonstrat..
Nov 27
2023
Mahoney et al., Open Forum Infectious Diseases, doi:10.1093/ofid/ofad500.1200 Preliminary Safety Results from a Phase 1 First in Human Study of VYD222: an Extended Half-Life Monoclonal Antibody (mAb) in Development for COVID-19 Prevention
Phase 1 RCT of monoclonal antibody VYD222 (pemivibart) in 12 healthy adults, showing no serious adverse events or infusion-related reactions through 14 days with 1500mg and through 2 days with 2500mg.
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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