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All Studies   Meta Analysis    Recent:   

The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study

Gao et al., PLOS ONE, doi:10.1371/journal.pone.0241540
Nov 2020  
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0 0.5 1 1.5 2+ Case 36% Improvement Relative Risk Sleep for COVID-19  Gao et al.  Prophylaxis Is better sleep beneficial for COVID-19? Retrospective 315 patients in China (February - March 2020) Fewer cases with higher quality sleep (p=0.038) c19early.org Gao et al., PLOS ONE, November 2020 Favors good sleep Favors control
Sleep for COVID-19
15th treatment shown to reduce risk in March 2021
 
*, now known with p = 0.0000000019 from 15 studies.
Lower risk for mortality, hospitalization, and cases.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
Case control study in China with 105 cases and 210 matched controls, showing COVID-19 cases associated with lack of sleep.
Study covers exercise and sleep.
risk of case, 35.9% lower, HR 0.64, p = 0.04, higher quality sleep 73 of 105 (69.5%) cases, 179 of 210 (85.2%) controls, NNT 4.6, inverted to make HR<1 favor higher quality sleep, case control OR, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Gao et al., 5 Nov 2020, retrospective, China, peer-reviewed, survey, median age 55.0, 11 authors, study period 10 February, 2020 - 1 March, 2020. Contact: guojiang@suda.edu.cn, canw@suda.edu.cn.
This PaperSleepAll
The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study
Chang Gao, Zhi Zhao, Fengyuan Li, Jia-Lin Liu, Hongyang Xu, Yuanying Zeng, Ling Yang, Jiahao Chen, Xiaoting Lu, Can Wang, Qiang Guo
PLOS ONE, doi:10.1371/journal.pone.0241540
Background Coronavirus disease 2019 (COVID-19) has spread to the world. Whether there is an association between lifestyle behaviors and the acquisition of COVID-19 remains unclear. Methods In this case-control study, we recruited 105 patients with SARS-CoV-2 infection as a case group from the Wuhan Tongji Hospital (Wuhan, China). For each case two control subjects were recruited. Participants were randomly selected from communities in Wuhan and matched for sex, age (± 2yrs), and pre-existing comorbidities (hypertension and diabetes). Results A total of 105 patients diagnosed with COVID-19 and 210 controls were included. Compared with control group, the case group had higher proportions of lack of sleep (30.5% vs. 14.8%, P = 0.001) and increased physical activities (56.2% vs. 32.9%, P < 0.001). And patients in the case group were more likely to have alopecia (28.6% vs. 10.0%, P < 0.001) than people from the control group. Overall, we found that lack of sleep [adjusted odds ratio (OR) 1.56, 95% confidence interval (CI) 1.03-2.39)], physical activities (� 5 times a week) (adjusted OR 2.05, 95%CI 1.39-3.02) and alopecia (adjusted OR 1.73, 95%CI 1.13-2.66) were independent risk factors for COVID-19 infection. Conversely, low-dose alcohol intake (<100g alcohol per week), hand hygiene, and fruits intake (daily) were significantly associated with a decrease in morbidity.
Supporting information Author Contributions Data curation: Chang Gao, Zhi Zhao, Jia-lin Liu, Hongyang Xu, Yuanying Zeng, Ling Yang, Jiahao Chen, Xiaoting Lu, Qiang Guo. Formal analysis: Chang Gao, Zhi Zhao, Fengyuan Li. Investigation: Chang Gao, Fengyuan Li. Supervision: Can Wang, Qiang Guo. Writing -original draft: Zhi Zhao, Fengyuan Li. Writing -review & editing: Qiang Guo.
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[]}], 'short-title': [], 'issued': {'date-parts': [[2020, 11, 5]]}, 'references-count': 40, 'journal-issue': {'issue': '11', 'published-online': {'date-parts': [[2020, 11, 5]]}}, 'URL': 'http://dx.doi.org/10.1371/journal.pone.0241540', 'relation': {}, 'ISSN': ['1932-6203'], 'subject': ['Multidisciplinary'], 'container-title-short': 'PLoS ONE', 'published': {'date-parts': [[2020, 11, 5]]}}
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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