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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Case -105% Improvement Relative Risk Exercise for COVID-19  Gao et al.  Prophylaxis Does physical activity reduce risk for COVID-19? Retrospective 315 patients in China (February - March 2020) More cases with higher activity levels (p=0.00031) c19early.org Gao et al., PLOS ONE, November 2020 Favors exercise Favors inactivity

The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study

Gao et al., PLOS ONE, doi:10.1371/journal.pone.0241540
Nov 2020  
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Exercise for COVID-19
9th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 66 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments. c19early.org
Case control study in China with 105 cases and 210 matched controls, showing COVID-19 cases associated with physical activity ≥5 times per week. Authors note that people may choose gyms for exercise in winter, leading to higher exposure risk.
Study covers exercise and sleep.
risk of case, 105.0% higher, HR 2.05, p < 0.001, high activity levels 59 of 105 (56.2%) cases, 69 of 210 (32.9%) controls, case control OR, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Gao et al., 5 Nov 2020, retrospective, China, peer-reviewed, survey, median age 55.0, 11 authors, study period 10 February, 2020 - 1 March, 2020. Contact: guojiang@suda.edu.cn, canw@suda.edu.cn.
This PaperExerciseAll
The impact of individual lifestyle and status on the acquisition of COVID-19: A case—Control study
Chang Gao, Zhi Zhao, Fengyuan Li, Jia-Lin Liu, Hongyang Xu, Yuanying Zeng, Ling Yang, Jiahao Chen, Xiaoting Lu, Can Wang, Qiang Guo
PLOS ONE, doi:10.1371/journal.pone.0241540
Background Coronavirus disease 2019 (COVID-19) has spread to the world. Whether there is an association between lifestyle behaviors and the acquisition of COVID-19 remains unclear. Methods In this case-control study, we recruited 105 patients with SARS-CoV-2 infection as a case group from the Wuhan Tongji Hospital (Wuhan, China). For each case two control subjects were recruited. Participants were randomly selected from communities in Wuhan and matched for sex, age (± 2yrs), and pre-existing comorbidities (hypertension and diabetes). Results A total of 105 patients diagnosed with COVID-19 and 210 controls were included. Compared with control group, the case group had higher proportions of lack of sleep (30.5% vs. 14.8%, P = 0.001) and increased physical activities (56.2% vs. 32.9%, P < 0.001). And patients in the case group were more likely to have alopecia (28.6% vs. 10.0%, P < 0.001) than people from the control group. Overall, we found that lack of sleep [adjusted odds ratio (OR) 1.56, 95% confidence interval (CI) 1.03-2.39)], physical activities (� 5 times a week) (adjusted OR 2.05, 95%CI 1.39-3.02) and alopecia (adjusted OR 1.73, 95%CI 1.13-2.66) were independent risk factors for COVID-19 infection. Conversely, low-dose alcohol intake (<100g alcohol per week), hand hygiene, and fruits intake (daily) were significantly associated with a decrease in morbidity.
Supporting information Author Contributions Data curation: Chang Gao, Zhi Zhao, Jia-lin Liu, Hongyang Xu, Yuanying Zeng, Ling Yang, Jiahao Chen, Xiaoting Lu, Qiang Guo. Formal analysis: Chang Gao, Zhi Zhao, Fengyuan Li. Investigation: Chang Gao, Fengyuan Li. Supervision: Can Wang, Qiang Guo. Writing -original draft: Zhi Zhao, Fengyuan Li. Writing -review & editing: Qiang Guo.
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