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Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh

Mohsin et al., Infection and Drug Resistance, doi:10.2147/IDR.S331470
Sep 2021  
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Severe case 38% Improvement Relative Risk Sleep for COVID-19  Mohsin et al.  Prophylaxis Is better sleep beneficial for COVID-19? Retrospective 1,500 patients in Bangladesh (November 2020 - April 2021) Lower severe cases with higher quality sleep (p=0.000031) Mohsin et al., Infection and Drug Resi.., Sep 2021 Favorsgood sleep Favorscontrol 0 0.5 1 1.5 2+
Sleep for COVID-19
15th treatment shown to reduce risk in March 2021
*, now with p = 0.0000000019 from 15 studies.
Lower risk for mortality, hospitalization, and cases.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 77 treatments.
Retrospective 1,500 COVID+ patients in Bangladesh, showing lower risk of severe cases with good sleep.
Study covers sleep and exercise.
risk of severe case, 37.9% lower, RR 0.62, p < 0.001, higher quality sleep 327 of 948 (34.5%), lower quality sleep 273 of 552 (49.5%), NNT 6.7, adjusted per study, inverted to make RR<1 favor higher quality sleep, odds ratio converted to relative risk, sleep disturbance, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mohsin et al., 30 Sep 2021, retrospective, Bangladesh, peer-reviewed, survey, 10 authors, study period November 2020 - April 2021.
This PaperSleepAll
Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh
Faroque Md Mohsin, Ridwana Nahrin, Tajrin Tahrin Tonmon, Maherun Nesa, Sharmin Ahmed Tithy, Shuvajit Saha, Mahmudul Mannan, Md Shahjalal, Mohammad Omar Faruque, Mohammad Delwer Hossain Hawlader
Infection and Drug Resistance, doi:10.2147/idr.s331470
Background: Severe COVID-19 infections have already taken more than 4 million lives worldwide. Factors, such as socio-demographics, comorbidities, lifestyles, environment, and so on, have been widely discussed to be associated with increased severity in many countries. The study aimed to determine the risk factors of severe-critical COVID-19 in Bangladesh. Methods: This was a comparative cross-sectional study among various types of COVID-19 patients (both hospitalized and non-hospitalized) confirmed by reverse transcription polymerase chain reaction (RT-PCR). We have selected 1500 COVID-19 positive patients using a convenient sampling technique and analyzed lifestyle and comorbidity-related data using IBM SPSS-23 statistical package software. Chi-square test and multinomial logistic regression were used to determine risk factors of life-threatening COVID-19 infection. Results: The mean age of the study participants was 43.23 (±15.48) years. The study identified several lifestyle-related factors and common commodities as risk factors for severe-critical COVID-19. The patient's age was one of the most important predictors, as people >59 years were at higher risk (AOR=18.223). Among other lifestyle factors, active smoking (AOR=1.482), exposure to secondary smoking (AOR=1.728), sleep disturbance (AOR=2.208) and attachment with SLT/alcohol/substance abuse (AOR=1.804) were identified as significant predictors for severe-critical COVID-19. Patients those were overweight/ obese (AOR=2.105), diabetic (AOR=4.286), hypertensive (AOR=3.363), CKD patients (AOR=8.317), asthma patients (AOR=2.152), CVD patients (AOR=7.747) were also at higher risk of severe-critical COVID-19 infection. Conclusion: This study has identified several vital lifestyles and comorbidity-related risk factors of severe-critical COVID-19. People who have these comorbidities should be under high protection, and risky lifestyles of the general population should modify through the proper educational campaign.
Disclosure The authors report no conflicts of interest in this work. Infection and Drug Resistance Dovepress
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