Alkalinization
Analgesics..
Antiandrogens..
Bromhexine
Budesonide
Cannabidiol
Colchicine
Conv. Plasma
Curcumin
Ensovibep
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Iota-carragee..
Ivermectin
Lactoferrin
Lifestyle..
Melatonin
Metformin
Molnupiravir
Monoclonals..
Nigella Sativa
Nitazoxanide
Nitric Oxide
Paxlovid
Peg.. Lambda
Povidone-Iod..
Quercetin
Remdesivir
Vitamins..
Zinc

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Other Treatments Global Adoption
COVID-19 treatment efficacy timeline
Evusheld Paxlovid Alkalinization APD Fluvoxamine Famotidine Molnupiravir Quercetin Bamlanivimab/e.. Budesonide Aspirin Probiotics Curcumin REGEN-COV Povidone-Iodine Nigella Sativa Melatonin Acetaminophen ↑risk Favipiravir Vitamin D Vitamin C Colchicine Antiandrogens Ivermectin Metformin Zinc HCQ 2020 2021 2022 Pooled outcomes Specific outcome RCT pooled RCT specific Statistically significant ≥10% improvement ≥3 studies c19early.org May 2023 Time when COVID-19 studies showed efficacy
Evusheld Paxlovid Alkalinization APD Fluvoxamine Famotidine Molnupiravir Quercetin Bamlanivimab/e.. Budesonide Aspirin Probiotics Curcumin REGEN-COV Povidone-Iodine Nigella Sativa Melatonin Acetaminophen ↑risk Favipiravir Vitamin D Vitamin C Colchicine Antiandrogens Ivermectin Metformin Zinc HCQ 2020 2021 2022 Pooled outcomes Specific outcome RCT pooled RCT specific Statistically significant ≥10% improvement ≥3 studies c19early.org May 2023 Time when COVID-19 studies showed efficacy
The time when studies indicated that treatments were effective, defined as statistically significant improvement of ≥10% from ≥3 studies. 0.9% of 3,817 proposed treatments have been identified as effective. Results reflect conditions as used in trials to date and depend on many factors including the population treated, treatment delay, and treatment regimen. Click the treatment name to see all studies, where the name of each study can be clicked on for the source paper. No treatment is 100% effective. Protocols typically combine multiple treatments which may be complementary and synergistic. Treatment efficacy may vary by variant, especially for monoclonal antibodies. All treatments have potential side effects which may exceed benefits. All practical, effective, and safe means should be used based on risk/benefit analysis. Submit Corrections or Updates
Currently, 36 of the treatments we analyze show statistically significant efficacy or harm, defined as ≥10% decreased risk or >0% increased risk from ≥3 studies.
RCT confirmation adds 4.4+ months delay. Of the 36 treatments with statistically significant efficacy/harm, 23 have been confirmed in RCTs, with a mean delay of 4.4 months. For the 13 unconfirmed treatments, 4 have zero RCTs to date. The point estimates for the remaining 9 are all consistent with the overall results (benefit or harm), with 8 showing >20%. The only treatment showing >10% efficacy for all studies, but <10% for RCTs is aspirin.
Specific outcome confirmation adds 3.1+ months delay. 97% of treatments showing statistically significant efficacy/harm with pooled effects have been confirmed with one or more specific outcomes, with a mean delay of 3.1 months.
Specific outcome confirmation for RCTs adds 2.9+ months delay. When restricting to RCTs only, 55% of treatments showing statistically significant efficacy/harm with pooled effects have been confirmed with one or more specific outcomes, with a mean delay of 2.9 months.
Pooled outcome analysis with the most serious outcome reported
Specific outcome analysis
Pooled outcome analysis for RCTs only
Specific outcome analysis for RCTs only
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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