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Ixekizumab for COVID-19
1 study with 32 patients
Hospital Icon Control
Hospital Icon Ixekizumab Serious Outcome Risk
No significant improvements are seen in meta analysis to date.
COVID-19 Ixekizumab studies. May 2025. c19early.org
0 0.5 1 1.5+ All studies -50% Mortality -50% RCTs -50% Late -50% Favorsixekizumab Favorscontrol
Apr 28
2022
Pimenta Bonifácio et al., Revista da Sociedade Brasileira de Medicina Tropical, doi:10.1590/0037-8682-0565-2022 (date from preprint) Efficacy and safety of Ixekizumab vs. low-dose IL-2 vs. Colchicine vs. standard of care in the treatment of patients hospitalized with moderate-to-critical COVID-19: A pilot randomized clinical trial (STRUCK: Survival Trial Using Cytokine Inhibitors)
50% higher mortality (p=1) and no change in improvement (p=1). Open label RCT late stage hospitalized patients in Brazil showing no significant difference with IL-2 or ixekizumab treatment. Mortality was lower and recovery was greater with colchicine, without statistical significance.
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