Tyr-Hyal for COVID-19

Tyr-Hyal has been reported as potentially beneficial for COVID-19 in the following study.
COVID-19 involves the interplay of 350+ viral and host proteins and factors providing many therapeutic targets. Scientists have proposed 10,000+ potential treatments. c19early.org analyzes 200+ treatments. We have not reviewed Tyr-Hyal in detail.
Aguilera-Rodriguez et al., Inhibition of SARS-CoV-2 3CLpro by chemically modified tyrosinase from Agaricus bisporus, RSC Medicinal Chemistry, doi:10.1039/D4MD00289J
A novel antiviral and non-cytotoxic bioconjugate of tyrosinase from Agaricus bisporus (AbTyr)-dextran-aspartic acid (6 kDa) polymer is developed.