Brexanolone for COVID-19: real-time analysis

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c19early.org

Brexanolone for COVID-19

1 study with 28 patients

Serious outcome risk

Brexanolone

Control

No significant improvements are seen in meta-analysis to date.

COVID-19 Brexanolone studies · October 2026

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−14%

Mortality (1)−14%

RCTs (1)−14%

Late (1)−14%

00.511.5+

← Brexanolone
reduces riskIncreased
risk →

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Jul 27 2022	Brown et al., NCT04537806	A Study of Brexanolone for Acute Respiratory Distress Syndrome Due to COVID-19
Jul 27 2022	14% higher mortality (p=1) and no change in progression (p=1). RCT 28 ventilated patients, showing no significant difference with brexanolone treatment.