Baricitinib for COVID-19
Baricitinib has been reported as potentially beneficial for early treatment of COVID-19. We have not reviewed these studies. See all other treatments.
Baricitinib restrains the immune dysregulation in patients with severe COVID-19, Journal of Clinical Investigation, doi:10.1172/JCI141772 ,
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality, Science Advances, doi:10.1126/sciadv.abe4724 ,
Baricitinib Therapy in Covid-19 Pneumonia — An Unmet Need Fulfilled, New England Journal of Medicine, doi:10.1056/NEJMe2034982 ,
Use of Janus kinase inhibitors in COVID-19: a prospective observational series in 522 individuals, Annals of the Rheumatic Diseases, doi:10.1136/annrheumdis-2021-220049 ,
Interaction of surface glycoprotein of SARS-CoV-2 variants of concern with potential drug candidates: A molecular docking study, F1000Research, doi:10.12688/f1000research.109586.1 ,
Potential inhibitors of SARS-CoV-2: recent advances, Journal of Drug Targeting, doi:10.1080/1061186X.2020.1853736 ,
Kinases as Potential Therapeutic Targets for Anti-coronaviral Therapy, Journal of Medicinal Chemistry, doi:10.1021/acs.jmedchem.1c00335 ,
Antivirals for COVID-19: A critical review, Clinical Epidemiology and Global Health, doi:10.1016/j.cegh.2020.07.006 ,
Drug repurposing and cytokine management in response to COVID-19: A review, International Immunopharmacology, doi:10.1016/j.intimp.2020.106947 ,
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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