Pep39 for COVID-19

Pep39 has been reported as potentially beneficial for COVID-19 in the following study.

COVID-19 involves the interplay of 350+ viral and host proteins and factors providing many therapeutic targets. Scientists have proposed 10,000+ potential treatments. c19early.org analyzes 200+ treatments. We have not reviewed pep39 in detail.

Study suggesting benefit with pep39

Thakkar et al., De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain, RSC Medicinal Chemistry, doi:10.1039/d3md00222e

Binding configuration of a de novo stapled peptide on SARS-CoV-2 spike protein, as predicted by molecular simulation. Stapled residues enhance peptide stability while interacting residues engage key amino acids on the protein receptor-binding domain.