Analgesics
Antiandrogens
Antihistamines
Budesonide
Colchicine
Conv. Plasma
Curcumin
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Monoclonals
Mpro inhibitors
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Quercetin
RdRp inhibitors
TMPRSS2 inh.
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
c19early.org COVID-19 treatment researchDimethyl fumarateDimethyl fumarate (more..)
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Fluvoxamine Meta Quercetin Meta
Hydroxychlor.. Meta
Ivermectin Meta
Thermotherapy Meta
Melatonin Meta
Metformin Meta

 
    
  
Dimethyl fumarate for COVID-19
1 study with >700 patients
Hospital Icon Control
Hospital Icon Dimethyl fumarate Serious Outcome Risk
No significant improvements are seen in meta analysis to date.
COVID-19 Dimethyl fumarate studies. Sep 2025. c19early.org
0 0.5 1 1.5+ All studies -3% Mortality -3% RCTs -3% Late -3% Favorsdimethyl fumarate Favorscontrol
Recent:
Horby.
Sep 2
Horby et al., medRxiv, doi:10.1101/2025.08.29.25334732 Long-term follow-up of treatment comparisons in RECOVERY: a randomised, open-label, platform trial for patients hospitalised with COVID-19
6-month followup of RECOVERY patients. Results are reported within the respective trials for each treatment.
Jan 31
2024
Horby et al., Nature Communications, doi:10.1038/s41467-023-43644-x Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
3% higher mortality (p=0.89), 20% higher ventilation (p=0.65), and 12% worse 7-point scale results (p=0.41). RCT 713 hospitalized COVID-19 patients showing no significant difference in clinical outcomes with dimethyl fumarate. 6-month results are from [Horby]
Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
  or use drag and drop   
Thanks for your feedback! Please search before submitting papers and note that studies are listed under the date they were first available, which may be the date of an earlier preprint.
Submit