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Voxvoganan for COVID-19
1 study with 23 patients
No significant improvements are seen in meta analysis to date.
COVID-19 Voxvoganan studies. Nov 2025. c19early.org
0 0.5 1 1.5+ All studies -29% Viral clearance -29% RCTs -29% Early -29% Favorsvoxvoganan Favorscontrol
Voxvoganan (LTX-109, Lytixar) is a synthetic cationic amphipathic antimicrobial peptidomimetic (small peptide-mimetic) designed to mimic host-defense peptides.
May 1
2022
Lütken et al., NCT04854928 A Double-blind, Placebo-controlled, Interventional Parallel Group Study to Evaluate the Antiviral Effect of a Single Nasal Application of LTX-109 3% Gel, in Comparison to Placebo Gel, in Subjects With COVID-19 Infection.
29% worse viral clearance (p=0.8). RCT 33 patients up to 6 days from symptom onset, showing no significant difference in short-term viral load change with LTX-109.
Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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