Voxvoganan for COVID-19
1 study with 23 patients
No significant improvements are seen in meta analysis to date.
COVID-19 Voxvoganan studies. Dec 2025. c19early.org
0 0.5 1 1.5+ All studies -29% Viral clearance -29% RCTs -29% Early -29% Favorsvoxvoganan Favorscontrol
Voxvoganan (LTX-109, Lytixar) is a synthetic cationic amphipathic antimicrobial peptidomimetic (small peptide-mimetic) designed to mimic host-defense peptides.
May 1
2022
Lütken et al., NCT04854928 A Double-blind, Placebo-controlled, Interventional Parallel Group Study to Evaluate the Antiviral Effect of a Single Nasal Application of LTX-109 3% Gel, in Comparison to Placebo Gel, in Subjects With COVID-19 Infection.
29% worse viral clearance (p=0.8). RCT 33 patients up to 6 days from symptom onset, showing no significant difference in short-term viral load change with LTX-109.