Sulbactam C6-tBuO for COVID-19

Sulbactam C6-tBuO has been reported as potentially beneficial for COVID-19 in the following study.

COVID-19 involves the interplay of 350+ viral and host proteins and factors providing many therapeutic targets. Scientists have proposed 10,000+ potential treatments. c19early.org analyzes 210+ treatments. We have not reviewed sulbactam C6-tBuO in detail.

Study suggesting benefit with sulbactam C6-tBuO

Muntean et al., C6-Alkoxy substituted penicillins are potent non-covalently binding inhibitors of the SARS-CoV-2 main protease, RSC Medicinal Chemistry, doi:10.1039/d5md00789e

Introduction of a C6-alkoxy group on the penicillin scaffold can alter the mechanism of SARS-CoV-2 main protease (M pro ) inhibition.