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Glenzocimab for COVID-19: real-time analysis

c19early.org

Glenzocimab for COVID-19

1 study with 62 patients

Serious outcome risk

Glenzocimab

Control

No significant improvements are seen in meta-analysis to date.

COVID-19 Glenzocimab studies · November 2026

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−60%

RCTs (1)−60%

Early (1)−60%

00.511.5+

← Glenzocimab
reduces riskIncreased
risk →

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Jun 17 2024	Pottecher et al., PLOS ONE, doi:10.1371/journal.pone.0302897	Targeting GPVI with glenzocimab in COVID-19 patients: Results from a randomized clinical trial
Jun 17 2024	RCT 61 hospitalized COVID-19 patients showing no significant difference in primary outcomes with glenzocimab (an anti-GPVI antibody) vs. placebo. Authors report glenzocimab showed a significant improvement in the NEWS-2 category at day 4,..

Most accessed treatments

Antiviral effects

Vitamins & Minerals

Host endosomal entry / trafficking

Dual-action mAbs

RdRp

Nasal & Oral Sprays / Rinses

Analgesics

Antiandrogens

Host targets and pathways

Inflammatory and immune modulation

Mpro (Gen 1)

Oxidative stress and cytoprotection

Lifestyles

TMPRSS2

Spike neutralization

Replication inhibition (target unresolved)

COVID-19 mAbs

Pleiotropic modulation

Attachment / entry inhibition

Mpro (Gen 2)

H1RAs

Nutrients and microbiome support

Host mAbs

IL-6 / IL-6R blockade

Physical and extracorporeal interventions

Natural products and extracts

Symptom management

Unconfirmed antiviral rationale

Lifestyle, behaviors, and exposure prevention

Other complication management

Mpro / 3CLpro

Host pyrimidine synthesis

Direct viral inactivation

Endothelial / vascular protection

Direct respiratory tract treatments

Other antibodies, proteins, peptides, cells, and RNA therapies

Secondary infection and coinfection management

Glenzocimab for COVID-19: real-time analysis