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Elderberry for COVID-19: real-time analysis of 2 studies

c19early.org
Elderberry for COVID-19
1 study with 171 patients
No significant improvements are seen in meta-analysis to date.
COVID-19 Elderberry studies · November 2026
Outcome (studies)
Improvement
Relative risk · 95% CI
All studies (1)−1%
RCTs (1)−1%
Early (1)−1%
00.511.5+
← Elderberry
reduces riskIncreased
risk →
Elderberry (Sambucus nigra) is an orally administered botanical dietary supplement proposed as potentially beneficial for SARS-CoV-2 via antiviral and immunomodulatory mechanisms. Recent:
Setz.
Apr 10
 Setz et al., Nutrients, doi:10.3390/nu18081205 Synergistic Virus Neutralizing Activities of European Black Elderberry Fruit Extract and Iota-Carrageenan Against SARS-CoV-2, Influenza A Virus and Respiratory Syncytial Virus
In vitro study showing synergistic antiviral activity of black elderberry fruit extract and iota-carrageenan against SARS-CoV-2 Omicron, influenza A, and respiratory syncytial virus.
May 16
2022
 Evans et al., NCT05489770 A Randomised, Single Blinded Study Investigating the Role of ' Black Elderberry (Sambucus Nigra) (Sambucol®) in the Treatment, Progression and Reduction of Symptoms in Participants With Coronavirus 19
1% worse recovery (p=0.37). RCT 204 COVID-19 patients showing no significant differences with Sambucol® black elderberry (Sambucus nigra) treatment. Treatment delay is unknown and may be too late. There was no restriction on the time from symptom onset, patients onl..