Goflikicept for COVID-19: real-time analysis

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c19early.org

Goflikicept for COVID-19

1 study with 247 patients

Serious outcome risk

Goflikicept

Control

No significant improvements are seen in meta-analysis to date.

COVID-19 Goflikicept studies · October 2026

Outcome (studies)

Improvement

Relative risk · 95% CI

All studies (1)−135%

Mortality (1)−135%

RCTs (1)−135%

Late (1)−135%

00.511.5+

← Goflikicept
reduces riskIncreased
risk →

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Jan 24 2022	Samsonov et al., NCT04380519	An International, Multicenter, Randomized, Double-blind, Adaptive Placebo-controlled Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe SARS-CoV-2 Infection (COVID-19)
Jan 24 2022	135% higher mortality (p=0.07) and no change in improvement (p=1). RCT 248 hospitalized patients showing higher mortality (p=0.07) with goflikicept (RPH-104).