Download Image
    
Share
  
Post
c19early.org
Mebendazole for COVID-19
3 studies with 411 patients
Serious outcome risk
Mebendazole
Control
Significantly lower risk for hospitalization, recovery, and viral clearance.
3 studies from 2 independent teams in 2 countries show significant benefit.
COVID-19 Mebendazole studies · October 2026
Covid Analysis Meta-analysis of mebendazole studies
Meta-analysis of mebendazole studies
Oct 14
2024
 Barda et al., Scientia Pharmaceutica, doi:10.3390/scipharm92040056 Evaluation of the Efficacy of Methylene Blue Administration in SARS-CoV-2-Affected Patients: A Proof-of-Concept Phase 2, Randomized, Placebo-Controlled, Single-Blind Clinical Trial
RCT with 29 mild COVID-19 outpatients in Switzerland, showing no significant difference with methylene blue treatment. There was a trend towards faster viral clearance. There were no serious adverse events. The trial was discontinued earl..
Apr 16
2024
 Agamah et al., ScienceOpen, doi:10.58647/DRUGARXIV.PR000010.v1 Network-based multi-omics-disease-drug associations reveal drug repurposing candidates for COVID-19 disease phases
In silico study identifying potential drugs beneficial for COVID-19 by integrating transcriptomics, proteomics, metabolomics, lipidomics, and drug data. Authors explore interactions between drugs, molecular features, and disease severity...
Dec 22
2023
 Bess et al., Frontiers in Pharmacology, doi:10.3389/fphar.2023.1297924 Identification of oral therapeutics using an AI platform against the virus responsible for COVID-19, SARS-CoV-2
In silico study showing potential benefit of mebendazole and zinc against SARS-CoV-2 according to an AI platform, eVir, designed to identify repurposed oral therapies. The software pipeline analyzes drug impacts on protein-protein network..
May 29
2023
 El-Tanani et al., Pharmaceuticals, doi:10.3390/ph16060799 Phase II, Double-Blinded, Randomized, Placebo-Controlled Clinical Trial Investigating the Efficacy of Mebendazole in the Management of Symptomatic COVID-19 Patients
RCT 69 outpatients in Jordan, showing improved viral clearance and CRP with mebendazole. Authors note that mebendazole, like ivermectin, has been shown to have antiviral activity against multiple viruses.
Dec 10
2022
 Galal et al., Advances in Virology, doi:10.1155/2022/3014686 The Use of Mebendazole in COVID-19 Patients: An Observational Retrospective Single Center Study
Retrospective 157 inpatients and 185 outpatients, showing improved recovery with mebendazole. For outpatients, the treatment group was younger (40 vs. 48). Mebendazole was offered to patients when ivermectin/HCQ were unavailable. The outp..
Dec 10
2022
 Galal et al., Advances in Virology, doi:10.1155/2022/3014686 The Use of Mebendazole in COVID-19 Patients: An Observational Retrospective Single Center Study
Retrospective 157 inpatients and 185 outpatients, showing improved recovery with mebendazole. For outpatients, the treatment group was younger (40 vs. 48). Mebendazole was offered to patients when ivermectin/HCQ were unavailable. The outp..