Control
Jan 31 |
et al., Global Advances in Integrative Medicine and Health, doi:10.1177/27536130251327134 | Efficient Control of IL-6, CRP and Ferritin in COVID-19 Patients With Two Variants of Beta-1,3-1,6 Glucans in Combination: An Open-Label, Prospective, Randomised Clinical Trial |
| 444% higher ventilation (p=0.2) and 444% higher ICU admission (p=0.2). RCT 40 COVID-19 patients showing significantly decreased IL-6 levels at day 7 with the combination of AFO-202 and N-163 beta-glucans compared to standard treatment, however there were no significant differences in clinical outcomes. | ||
Sep 25 2021 |
et al., Biomedicine & Pharmacotherapy, doi:10.1016/j.biopha.2021.112243 | Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study |
| no change in oxygen therapy (p=1) and 12% longer hospitalization. RCT 24 hospitalized COVID-19 patients showing potential benefit with Aureobasidium pullulans beta-glucan supplementation. While inflammatory markers (IL-6, D-dimer) initially decreased in all groups by day 15, they rebounded to abnormal l.. | ||
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