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Estetrol for COVID-19
1 study with 171 patients
Hospital Icon Control
Hospital Icon Estetrol Serious Outcome Risk
No significant improvements are seen in meta analysis to date.
COVID-19 Estetrol studies. Nov 2025. c19early.org
0 0.5 1 1.5+ All studies -102% Mortality -102% RCTs -102% Late -102% Favorsestetrol Favorscontrol
Jun 8
2023
 Foidart et al., Journal of Clinical Medicine, doi:10.3390/jcm12123928 Estetrol Is Safe and Well Tolerated during Treatment of Hospitalized Men and Women with Moderate COVID-19 in a Randomized, Double-Blind Study
102% higher mortality (p=0.33) and 117% worse recovery (p=0.07). RCT 175 hospitalized patients with moderate COVID-19 showing no significant benefit with estetrol (E4) treatment.