Summary of COVID-19 estetrol studies

1. Foidart et al., Estetrol Is Safe and Well Tolerated during Treatment of Hospitalized Men and Women with Moderate COVID-19 in a Randomized, Double-Blind Study

171 patient estetrol late treatment RCT: 102% higher mortality (p=0.33) and 117% worse recovery (p=0.07).
RCT 175 hospitalized patients with moderate COVID-19 showing no significant benefit with estetrol (E4) treatment.
Jun 2023, J. Clinical Medicine, https://www.mdpi.com/2077-0383/12/12/3928, https://c19p.org/foidart