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COVID-19: healthy lifestyles reduce risk

• Healthy lifestyles reduce COVID-19 severity

We do not provide medical advice. No treatment is 100% effective, and all may have side effects. Protocols combine multiple treatments. Consult a qualified physician for personalized risk/benefit analysis.
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Efficacy confidence - lifestyles
Dietp<0.0000000001
Exercisep<0.0000000001
Sleepp=0.0000000008
Sunlightp=0.00005
Efficacy confirmed October 2020 (exercise)(a),1
P-values indicate the confidence that studies show a significant effect. p=0.05 is the typical threshold for significance in scientific papers, with lower values indicating higher confidence. These healthy lifestyles show lower risk for COVID-19. See the individual analyses for details of efficacy for specific outcomes and conditions.
Healthy lifestyles reduce risk. Across 119 studies, exercise, sunlight, a healthy diet, and good sleep have all shown statistically significant efficacy for SARS-CoV-2, just as they have for other viruses2-5. They also all have connections to other treatments found effective:
Sunlight6-11 increases nitric oxide and vitamin D, and helps regulate the circadian rhythm, which supports immune health. Sunlight may increase melatonin production at night, and directly inactivate SARS-CoV-212.
A healthy diet13-43 contains many nutrients shown to be beneficial, enhances immune system function, and supports a healthy gut microbiome.
Good sleep40,44-59 can improve the absorption, metabolism, and utilization of nutrients, and is crucial for the proper functioning of the immune system. During sleep, the body produces and releases cytokines and T cells that help fight infections, reduce inflammation, and create immune memory.
Exercise40,57,60-126 increases nitric oxide, reduces chronic inflammation, improves cardiovascular health, improves comorbidities, and enhances lung function.
Healthy lifestyles may reduce risk even after infection. Most studies examine outcomes based on lifestyles before infection. What about during infection? Logically, healthy lifestyles may still be beneficial, especially prior to later stage disease, and within limits(b). Hossain et al.127 predict lower mortality for increased sunlight exposure before about 7 days after infection. In hospitalized patients, Fernandez et al.60 show lower mortality with exercise, and Pereira et al.6 show faster recovery with near-infrared light.
Pandemic measures negatively affected lifestyles. A study of 1.2 million people worldwide showed a significant decline in physical activity during the pandemic128. A meta analysis found that 25 of 25 studies showed a decrease in physical activity129. Adults at high risk of severe COVID-19 were more likely to be physically inactive130. There were unfavorable changes in diet131,132 and sleep132,133. Lockdowns increased the prevalence of vitamin D deficiency134,135. A review showed negative effects for mental health, physical activity, and obesity136, and people with poor health status may have been more likely to have unfavorable lifestyle changes, compounding risk137. Fear, stress, and loneliness increase risk for poor COVID-19 outcomes138, and were amplified by the isolation and uncertainty of pandemic measures, along with inaccurate depictions of risk and available treatments. The pandemic was associated with increased weight and higher prevalence of hypertension in adolescents in the USA139, and a substantial increase in global hunger and malnutrition140. Overweight and underweight both increase risk for COVID-19141.
Defined as ≥3 studies showing ≥10% improvement or >0% harm with statistical significance in meta analysis.
For example, vigorous exercise may be harmful depending on condition.
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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