UV and violet light can Neutralize SARS-CoV-2 Infectivity
et al., Journal of Photochemistry and Photobiology, doi:10.1016/j.jpap.2021.100107
, UV and violet light can Neutralize SARS-CoV-2 Infectivity, Journal of Photochemistry and Photobiology, doi:10.1016/j.jpap.2021.100107
In Vitro study showing that UV irradiation is effective for SARS-CoV-2 inhibition at multiple wavelengths including UV-A and violet light.
Biasin et al., 30 Jun 2022, peer-reviewed, 13 authors.
Contact:
mario.clerici@unimi.it.
UV and violet light can Neutralize SARS-CoV-2 Infectivity
Journal of Photochemistry and Photobiology, doi:10.1016/j.jpap.2021.100107
We performed an in-depth analysis of the virucidal effect of discrete wavelengths: UV-C (278 nm), UV-B (308 nm), UV-A (366 nm) and violet (405 nm) on SARS-CoV-2. By using a highly infectious titer of SARS-CoV-2 we observed that the violet light-dose resulting in a 2-log viral inactivation is only 10 4 times less efficient than UV-C light. Moreover, by qPCR (quantitative Polymerase chain reaction) and fluorescence in situ hybridization (FISH) approach we verified that the viral titer typically found in the sputum of COVID-19 patients can be completely inactivated by the long UV-wavelengths corresponding to UV-A and UV-B solar irradiation. The comparison of the UV action spectrum on SARS-CoV-2 to previous results obtained on other pathogens suggests that RNA viruses might be particularly sensitive to long UV wavelengths. Our data extend previous results showing that SARS-CoV-2 is highly susceptible to UV light and offer an explanation to the reduced incidence of SARS-CoV-2 infection seen in the summer season.
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