In Vitro study showing high infectious titer SARS-CoV-2 completely inactivated by UVC irradiation in 9 minutes. The UVC dose required for complete inactivation was 1,048 mJ/c.
Heilingloh et al., 31 Oct 2020, Germany, peer-reviewed, 12 authors.
Contact:
adalbert.krawczyk@uni-due.de.
Susceptibility of SARS-CoV-2 to UV irradiation
Christiane Silke Heilingloh, Ulrich Wilhelm Aufderhorst, Leonie Schipper, PhD Ulf Dittmer, MD Oliver Witzke, Dongliang Yang, Xin Zheng, Kathrin Sutter, PhD Mirko Trilling, MSc Mira Alt, Eike Steinmann, PhD Adalbert Krawczyk
American Journal of Infection Control, doi:10.1016/j.ajic.2020.07.031
The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 £ 10 6 TCID 50 /mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm 2 . UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.
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