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COVID-19 in individuals adapted to aerobic exercise

Tret'yakov et al., Pulmonologiya, doi:10.18093/0869-0189-2020-30-5-553-560
Oct 2020  
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Severe case 98% Improvement Relative Risk Exercise for COVID-19  Tret'yakov et al.  Prophylaxis Does physical activity reduce risk for COVID-19? Retrospective 293 patients in Russia Lower severe cases with higher activity levels (p=0.0067) c19early.org Tret'yakov et al., Pulmonologiya, October 2020 Favorsexercise Favorsinactivity 0 0.5 1 1.5 2+
Exercise for COVID-19
9th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 68 studies.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19early.org
Retrospective 293 COVID+ patients in Russia, showing lower risk of severe COVID-19 for individuals who regularly practice aerobic training in unadjusted results.
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of severe case, 98.3% lower, RR 0.02, p = 0.007, high activity levels 0 of 27 (0.0%), low activity levels 53 of 266 (19.9%), NNT 5.0, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Tret'yakov et al., 26 Oct 2020, retrospective, Russia, peer-reviewed, 8 authors.
This PaperExerciseAll
COVID-19 in individuals adapted to aerobic exercise
Andrey Yu. Tret'yakov, Svetlana P Zakharchenko, L V Romasenko, Alena V Dyatlova, Aleksandra V Zhabskaya, Oleg V Ermilov, Mikhail A Tret'yakov, D D Chentsova
PULMONOLOGIYA, doi:10.18093/0869-0189-2020-30-5-553-560
Analysis of COVID-19 features in individuals who regularly practice aerobic training. Methods. Asymptomatic persons and patients with COVID-19 older than 30 years, 293 people (180 men and 113 women), 214 of them -inhabitants of the Moscow region (the beginning of the sampling -2 nd decade of April 2020) and 79 -inhabitants of the Belgorod region (the beginning of the sampling -2 nd decade of May 2020), adapted (27 people -1 st group) and unadapted (266 -control group) to aerobic training (AT). Computer tomography of the chest, RNA test for SARS-CoV-2 in smears from the nasopharynx-oropharynx, the clinical blood sample and level of antibodies to SARS-CoV-2 were studied. The criterion for adaptation to aerobic loads was considered compliance with the rules of the American Heart Association, 2008. Results. Adapted to AT individuals, in contrast to the control group, characterized with the prevalence of asymptomatic (p = 0.045) and absence of severe forms of COVID-19, limited cataral simptoms of the disease (p < 0.001), rare pneumonia with absence (1) or presence (2) of acute respiratory failure (p 1 = 0,028; p 2 = 0,034), along with lower prevalence of diseases, potentiating this infection (p = 0.03). Conclusion. Patients adapted to AT have less severe course of COVID-19.
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Asymptomatic persons and patients with COVID-19 older than 30 ' 'years, 293 people (180 men and 113 women), 214 of them – inhabitants of the Moscow region ' '(the beginning of the sampling – 2<jats:sup>nd</jats:sup> decade of April 2020) and 79 – ' 'inhabitants of the Belgorod region (the beginning of the sampling – 2<jats:sup>nd</jats:sup> ' 'decade of May 2020), adapted (27 people 1<jats:sup>st</jats:sup> group) and unadapted (266 – ' 'control group) to aerobic training (AT). Computer tomography of the chest, RNA test for ' 'SARS-CoV-2 in smears from the nasopharynx-oropharynx, the clinical blood sample and level of ' 'antibodies to SARS-CoV-2 were studied. The criterion for adaptation to aerobic loads was ' 'considered compliance with the rules of the American Heart Association, 2008. ' '<jats:bold>Results</jats:bold>. Adapted to AT individuals, in contrast to the control group, ' 'characterized with the prevalence of asymptomatic (<jats:italic>p</jats:italic> = 0.045) and ' 'absence of severe forms of COVID-19, limited cataral simptoms of the disease ' '(<jats:italic>p</jats:italic> &lt; 0.001), rare pneumonia with absence (1) or presence (2) of ' 'acute respiratory failure (<jats:italic>p</jats:italic><jats:sub>1</jats:sub> = 0,028; ' '<jats:italic>p</jats:italic><jats:sub>2</jats:sub> = 0,034), along with lower prevalence of ' 'diseases, potentiating this infection (<jats:italic>p</jats:italic> = 0.03). ' '<jats:bold>Conclusion</jats:bold>. Patients adapted to AT have less severe course of ' 'COVID-19.</jats:p>', 'DOI': '10.18093/0869-0189-2020-30-5-553-560', 'type': 'journal-article', 'created': { 'date-parts': [[2020, 10, 26]], 'date-time': '2020-10-26T14:30:56Z', 'timestamp': 1603722656000}, 'page': '553-560', 'update-policy': 'http://dx.doi.org/10.18093/0869-0189-crossmark', 'source': 'Crossref', 'is-referenced-by-count': 2, 'title': 'COVID-19 in individuals adapted to aerobic exercise', 'prefix': '10.18093', 'volume': '30', 'author': [ { 'given': 'A. Yu.', 'family': "Tret'yakov", 'sequence': 'first', 'affiliation': [ { 'name': 'Federal Belgorod National Research University, Ministry of ' 'Education and Science of Russia'}]}, { 'given': 'S. P.', 'family': 'Zakharchenko', 'sequence': 'additional', 'affiliation': [ { 'name': 'Federal Belgorod National Research University, Ministry of ' 'Education and Science of Russia'}]}, { 'given': 'L. 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DOI: ' '10.1186/s12931-019-0978-1.', 'DOI': '10.1186/s12931-019-0978-1'}], 'container-title': 'PULMONOLOGIYA', 'original-title': [], 'link': [ { 'URL': 'https://journal.pulmonology.ru/pulm/article/viewFile/1376/1753', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'text-mining'}], 'deposited': { 'date-parts': [[2020, 10, 26]], 'date-time': '2020-10-26T14:36:41Z', 'timestamp': 1603723001000}, 'score': 1, 'resource': {'primary': {'URL': 'https://journal.pulmonology.ru/pulm/article/view/1376'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2020, 10, 26]]}, 'references-count': 25, 'journal-issue': {'issue': '5', 'published-online': {'date-parts': [[2020, 10, 26]]}}, 'URL': 'http://dx.doi.org/10.18093/0869-0189-2020-30-5-553-560', 'relation': {}, 'ISSN': ['2541-9617', '0869-0189'], 'subject': ['Pulmonary and Respiratory Medicine'], 'container-title-short': 'Pulʹmonologiâ (Mosk.)', 'published': {'date-parts': [[2020, 10, 26]]}}
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