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0 0.5 1 1.5 2+ PASC, before and during 26% Improvement Relative Risk PASC, during 17% Exercise  Feter et al.  Prophylaxis  LONG COVID Does physical activity reduce the risk of Long COVID (PASC)? Retrospective 237 patients in Brazil Lower PASC with higher activity levels (p=0.016) Feter et al., Public Health, June 2023 Favors exercise Favors inactivity

Physical activity and long COVID: findings from the Prospective Study About Mental and Physical Health in Adults cohort

Feter et al., Public Health, doi:10.1016/j.puhe.2023.05.011
Jun 2023  
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Analysis of 237 COVID-19 patients in Brazil, showing lower risk of long COVID with physical activity.
risk of PASC, 26.0% lower, RR 0.74, p = 0.02, high activity levels 52, low activity levels 95, adjusted per study, before and during pandemic, multivariable.
risk of PASC, 17.0% lower, RR 0.83, p = 0.04, high activity levels 67, low activity levels 170, adjusted per study, during pandemic, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Feter et al., 13 Jun 2023, retrospective, Brazil, peer-reviewed, survey, mean age 37.1, 17 authors.
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Physical activity and long COVID: findings from the Prospective Study About Mental and Physical Health in Adults cohort
N Feter, E L Caputo, F M Delpino, J S Leite, L S Da Silva, I De Almeida Paz, J Q Santos Rocha, Y P Vieira, N Schröeder, C N Da Silva, J C Baptista Gonçalves, H Da Costa Pereira, T A Barbosa, J Cassuriaga, M C Da Silva, F F Reichert, A J Rombaldi
Public Health, doi:10.1016/j.puhe.2023.05.011
Objectives: The study investigated the longitudinal association between physical activity and the risk of long COVID in patients who recovered from COVID-19 infection. Study design: We analyzed longitudinal data of the Prospective Study About Mental and Physical Health cohort, a prospective cohort study with adults living in Southern Brazil. Methods: Participants responded to an online, self-administered questionnaire in June 2020 (wave 1) and June 2022 (wave 4). Only participants who self-reported a positive test for COVID-19 were included. Physical activity was assessed before (wave 1, retrospectively) and during the pandemic (wave 1). Long COVID was assessed in wave 4 and defined as any post-COVID-19 symptoms that persisted for at least 3 months after infection. Results: A total of 237 participants (75.1% women; mean age [standard deviation]: 37.1 [12.3]) were included in this study. The prevalence of physical inactivity in baseline was 71.7%, whereas 76.4% were classified with long COVID in wave 4. In the multivariate analysis, physical activity during the pandemic was associated with a reduced likelihood of long COVID (prevalence ratio [PR]: 0.83; 95% confidence interval [CI]: 0.69e0.99) and a reduced duration of long COVID symptoms (odds ratio: 0.44; 95% CI: 0.26 e0.75). Participants who remained physically active from before to during the pandemic were less likely to report long COVID (PR: 0.74; 95% CI: 0.58e0.95), fatigue (PR: 0.49; 95% CI: 0.32e0.76), neurological complications (PR: 0.47; 95% CI: 0.27e0.80), cough (PR: 0.40; 95% CI: 0.22e0.71), and loss of sense of smell or taste (PR: 0.43; 95% CI: 0.21e0.87) as symptom-specific long COVID. Conclusion: Physical activity practice was associated with reduced risk of long COVID in adults.
Ethical approval The ethics board approved the study from the Physical Education Faculty (Universidade Federal de Pelotas, Brazil; CAAE: 31906920.7.0000.5313). Competing interests None declared. Appendix A. Supplementary data Supplementary data to this article can be found online at
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