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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 89% Improvement Relative Risk Hospitalization 28% Exercise for COVID-19  Halabchi et al.  Prophylaxis Does physical activity reduce risk for COVID-19? Retrospective 4,694 patients in Iran Lower hospitalization with higher activity levels (p=0.044) c19early.org Halabchi et al., J. Physical Activity .., Dec 2020 Favors exercise Favors inactivity

Regular Sports Participation as a Potential Predictor of Better Clinical Outcome in Adult Patients With COVID-19: A Large Cross-Sectional Study

Halabchi et al., Journal of Physical Activity and Health, doi:10.1123/jpah.2020-0392
Dec 2020  
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Exercise for COVID-19
9th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 66 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19early.org
Retrospective 4,694 COVID-19 patients in Iran, showing lower risk of hospitalization and mortality with regular sports participation.
risk of death, 88.8% lower, RR 0.11, p = 0.08, high activity levels 0 of 249 (0.0%), low activity levels 79 of 4,445 (1.8%), NNT 56, adjusted per study, odds ratio converted to relative risk, multivariable.
risk of hospitalization, 28.3% lower, RR 0.72, p = 0.04, high activity levels 30 of 249 (12.0%), low activity levels 878 of 4,445 (19.8%), adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Halabchi et al., 1 Dec 2020, retrospective, Iran, peer-reviewed, 8 authors.
This PaperExerciseAll
{ 'DOI': '10.1123/jpah.2020-0392', 'ISSN': ['1543-3080', '1543-5474'], 'URL': 'http://dx.doi.org/10.1123/jpah.2020-0392', 'abstract': '<jats:p><jats:bold>Purpose</jats:bold>: To compare the severity outcomes of COVID-19 disease ' 'between patients with and without regular sports participation. ' '<jats:bold>Methods</jats:bold>: In a cross-sectional study, the authors investigated all ' 'patients who visited the emergency department of Imam Khomeini hospital with signs and ' 'symptoms of COVID-19 from February 20 to April 20, 2020. Then the authors assessed all ' 'patient outcomes (outpatient vs hospitalization or death). Finally, the authors compared the ' 'outcomes between athletes with regular sports participation and others, adjusting for ' 'confounding factors of age and sex. <jats:bold>Results</jats:bold>: Of all 4694 adult ' 'patients, 249 individuals (137 males and 112 females with mean [SD] age of 36.45 [9.77]\xa0y) ' 'had regular participation in different sport disciplines. Overall, 30 (12%) athletes were ' 'hospitalized or died (30 and 0, respectively) compared with 957 (21.5%) nonathletes (878 and ' '79, respectively). Athletes with regular sports participation were 1.49 times less likely to ' 'be hospitalized (<jats:italic>P</jats:italic>\u2009=\u2009.044). ' '<jats:bold>Conclusions</jats:bold>: Regular sports participation may positively affect the ' 'clinical outcome, regardless of confounding factors of age and sex. The probability of ' 'hospitalization in athletes with regular sports participation was 33% lower than nonathletes. ' 'However, more longitudinal studies are needed to determine the causal effects.</jats:p>', 'author': [ {'affiliation': [], 'family': 'Halabchi', 'given': 'Farzin', 'sequence': 'first'}, {'affiliation': [], 'family': 'Mazaheri', 'given': 'Reza', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Sabeti', 'given': 'Khashayar', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Yunesian', 'given': 'Masoud', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Alizadeh', 'given': 'Zahra', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Ahmadinejad', 'given': 'Zahra', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Aghili', 'given': 'Seyed Mojtaba', 'sequence': 'additional'}, {'affiliation': [], 'family': 'Tavakol', 'given': 'Zahra', 'sequence': 'additional'}], 'container-title': ['Journal of Physical Activity and Health'], 'content-domain': {'crossmark-restriction': False, 'domain': []}, 'created': {'date-parts': [[2020, 12, 1]], 'date-time': '2020-12-01T15:28:16Z', 'timestamp': 1606836496000}, 'deposited': { 'date-parts': [[2021, 2, 5]], 'date-time': '2021-02-05T07:14:31Z', 'timestamp': 1612509271000}, 'indexed': {'date-parts': [[2022, 3, 30]], 'date-time': '2022-03-30T03:52:49Z', 'timestamp': 1648612369654}, 'is-referenced-by-count': 5, 'issn-type': [{'type': 'print', 'value': '1543-3080'}, {'type': 'electronic', 'value': '1543-5474'}], 'issue': '1', 'issued': {'date-parts': [[2021, 1, 1]]}, 'journal-issue': {'issue': '1'}, 'link': [ { 'URL': 'https://journals.humankinetics.com/view/journals/jpah/18/1/article-p8.xml', 'content-type': 'text/html', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://journals.humankinetics.com/downloadpdf/journals/jpah/18/1/article-p8.xml', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'member': '100', 'original-title': [], 'page': '8-12', 'prefix': '10.1123', 'published': {'date-parts': [[2021, 1, 1]]}, 'published-print': {'date-parts': [[2021, 1, 1]]}, 'publisher': 'Human Kinetics', 'reference-count': 60, 'references-count': 60, 'relation': {}, 'resource': { 'primary': { 'URL': 'https://journals.humankinetics.com/view/journals/jpah/18/1/article-p8.xml'}}, 'score': 1, 'short-container-title': [], 'short-title': [], 'source': 'Crossref', 'subject': ['Orthopedics and Sports Medicine'], 'subtitle': [], 'title': [ 'Regular Sports Participation as a Potential Predictor of Better Clinical Outcome in Adult ' 'Patients With COVID-19: A Large Cross-Sectional Study'], 'type': 'journal-article', 'volume': '18'}
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