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0 0.5 1 1.5 2+ Case 7% Improvement Relative Risk Exercise for COVID-19  Akbar et al.  Prophylaxis Does physical activity reduce risk for COVID-19? Retrospective 10,000 patients in Qatar No significant difference in cases Akbar et al., MDPI AG, November 2023 Favors exercise Favors inactivity

Association between lifestyle factors and COVID-19: findings from Qatar Biobank

Nov 2023  
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Retrospective 10,000 adults in Qatar, showing lower risk of COVID-19 cases with increased leisure time physical activity, without statistical significance. Authors do not analyze COVID-19 severity.
This study includes vitamin B9, vitamin C, diet, exercise, and vitamin D.
risk of case, 7.0% lower, OR 0.93, p = 0.40, high activity levels 3,333, low activity levels 3,333, adjusted per study, T3 vs. T1, multivariable, model 2, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Akbar et al., 7 Nov 2023, retrospective, Qatar, preprint, mean age 40.3, 9 authors.
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Association between lifestyle factors and COVID-19: findings from Qatar Biobank
Zoha Akbar, Hasna H Kunhipurayil, Jessica Saliba, Jamil Ahmad, Layla Al-Mansoori, Hebah A Al-Khatib, Asmaa A Al Thani, Zumin Shi, Abdullah A Shaito
Coronavirus Disease 2019 (COVID-19) exhibits a significant variation in presentation of symptoms ranging from mild to severe life-threatening symptoms, including death. COVID-19 infection susceptibility has been linked with various covariates, but studies in Qatar are limited. Data from Qatar Biobank (QBB) (n = 10,000; 18-to 79-year-old adults) were analyzed for associations between sociodemographic and lifestyle factors and susceptibility to COVID-19. Logistic regression was used to assess the associations between COVID-19 and age, gender, body mass index (BMI), smoking status, education level, dietary patterns, supplement use, physical activity, history of bariatric surgery, diabetes, and hypertension. In total, 10.5% (n = 1045) of the participants had COVID-19. Compared to non-smokers, current and ex-smokers had lower odds of having COVID-19 (odds ratio [OR]= 0.55; 95% CI: 0.44-0.68 and OR= 0.70; 95% CI: 0.57-0.86, respectively). Vitamin D supplement use was associated with an 18% reduction of the likelihood of contracting COVID-19 (OR = 0.82; 95% CI: 0.69-0.97). Obesity (BMI ≥30 kg/m 2 ), history of bariatric surgery and higher adherence to the modern dietary pattern-characterized by consumption of foods high in saturated fat and refined carbohydrates-were positively associated with COVID-19. Our findings indicate that adopting a healthy lifestyle may be helpful in the prevention of COVID-19 infection.
Author Contributions: Conceptualization, A.A.S. and Z.S.; investigation, A.A.S., Z.S., Z.A., J.S.; resources, A.A.S., Z.S.; writing-original draft preparation, A.A.S., Z.S., Z.A., ; writing-review and editing, All Authors; Supervision, A.A.S., Z.S., A.A.A.T; project administration, A.A.S.; funding acquisition, A.A.S. All authors have read and agreed to the published version of the manuscript. Funding: Qatar National Research Fund (QNRF) grant number RRC02-0807-210,022 to A.A.S. The funding source (QNRF) had no role in study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the article for publication. Institutional Review Board
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