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0 0.5 1 1.5 2+ Case 14% Improvement Relative Risk Vitamin C for COVID-19  Akbar et al.  Prophylaxis Does vitamin C reduce COVID-19 infections? Retrospective 10,000 patients in Qatar (March - September 2020) Fewer cases with vitamin C (not stat. sig., p=0.29) c19early.org Akbar et al., Nutrients, November 2023 Favors vitamin C Favors control

The Association between Lifestyle Factors and COVID-19: Findings from Qatar Biobank

Akbar et al., Nutrients, doi:10.3390/nu16071037
Nov 2023  
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Vitamin C for COVID-19
6th treatment shown to reduce risk in September 2020
 
*, now known with p = 0.000000087 from 70 studies, recognized in 11 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19early.org
Retrospective 10,000 adults in Qatar, showing lower risk of COVID-19 cases with vitamin C supplementation, without statistical significance. Authors do not analyze COVID-19 severity.
This is the 68th of 70 COVID-19 controlled studies for vitamin C, which collectively show efficacy with p=0.000000087 (1 in 11 million).
21 studies are RCTs, which show efficacy with p=0.0012.
Study covers vitamin B9, vitamin C, diet, exercise, and vitamin D.
risk of case, 14.0% lower, OR 0.86, p = 0.29, treatment 665, control 9,335, adjusted per study, multivariable, model 2, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Akbar et al., 7 Nov 2023, retrospective, Qatar, peer-reviewed, mean age 40.3, 9 authors, study period March 2020 - September 2020. Contact: za1404491@student.qu.edu.qa, zumin@qu.edu.qa, almansouri@qu.edu.qa, h.alkhatib@qu.edu.qa, aaja@qu.edu.qa, abdshaito@qu.edu.qa, jessica.saliba@balamand.edu.lb, jamilnidal@gmail.com.
This PaperVitamin CAll
Association between lifestyle factors and COVID-19: findings from Qatar Biobank
Zoha Akbar, Hasna H Kunhipurayil, Jessica Saliba, Jamil Ahmad, Layla Al-Mansoori, Hebah A Al-Khatib, Asmaa A Al Thani, Zumin Shi, Abdullah A Shaito
doi:10.20944/preprints202311.0330.v1
Coronavirus Disease 2019 (COVID-19) exhibits a significant variation in presentation of symptoms ranging from mild to severe life-threatening symptoms, including death. COVID-19 infection susceptibility has been linked with various covariates, but studies in Qatar are limited. Data from Qatar Biobank (QBB) (n = 10,000; 18-to 79-year-old adults) were analyzed for associations between sociodemographic and lifestyle factors and susceptibility to COVID-19. Logistic regression was used to assess the associations between COVID-19 and age, gender, body mass index (BMI), smoking status, education level, dietary patterns, supplement use, physical activity, history of bariatric surgery, diabetes, and hypertension. In total, 10.5% (n = 1045) of the participants had COVID-19. Compared to non-smokers, current and ex-smokers had lower odds of having COVID-19 (odds ratio [OR]= 0.55; 95% CI: 0.44-0.68 and OR= 0.70; 95% CI: 0.57-0.86, respectively). Vitamin D supplement use was associated with an 18% reduction of the likelihood of contracting COVID-19 (OR = 0.82; 95% CI: 0.69-0.97). Obesity (BMI ≥30 kg/m 2 ), history of bariatric surgery and higher adherence to the modern dietary pattern-characterized by consumption of foods high in saturated fat and refined carbohydrates-were positively associated with COVID-19. Our findings indicate that adopting a healthy lifestyle may be helpful in the prevention of COVID-19 infection.
Author Contributions: Conceptualization, A.A.S. and Z.S.; investigation, A.A.S., Z.S., Z.A., J.S.; resources, A.A.S., Z.S.; writing-original draft preparation, A.A.S., Z.S., Z.A., ; writing-review and editing, All Authors; Supervision, A.A.S., Z.S., A.A.A.T; project administration, A.A.S.; funding acquisition, A.A.S. All authors have read and agreed to the published version of the manuscript. Funding: Qatar National Research Fund (QNRF) grant number RRC02-0807-210,022 to A.A.S. The funding source (QNRF) had no role in study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the article for publication. Institutional Review Board
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