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The Association between Lifestyle Factors and COVID-19: Findings from Qatar Biobank

Akbar et al., Nutrients, doi:10.3390/nu16071037
Nov 2023  
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Case 19% Improvement Relative Risk Vitamin D for COVID-19  Akbar et al.  Prophylaxis Does vitamin D reduce COVID-19 infections? Retrospective 10,000 patients in Qatar (March - September 2020) Fewer cases with vitamin D (p=0.018) c19early.org Akbar et al., Nutrients, November 2023 Favorsvitamin D Favorscontrol 0 0.5 1 1.5 2+
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 79 treatments. c19early.org
Retrospective 10,000 adults in Qatar, showing lower risk of COVID-19 cases with vitamin D supplementation. Authors do not analyze COVID-19 severity.
This is the 118th of 122 COVID-19 controlled studies for vitamin D, which collectively show efficacy with p<0.0000000001 (1 in 587 sextillion).
30 studies are RCTs, which show efficacy with p=0.0000032.
Study covers vitamin B9, vitamin C, diet, exercise, and vitamin D.
risk of case, 19.0% lower, OR 0.81, p = 0.02, treatment 2,402, control 7,598, adjusted per study, multivariable, model 2, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Akbar et al., 7 Nov 2023, retrospective, Qatar, peer-reviewed, mean age 40.3, 9 authors, study period March 2020 - September 2020, dosage not specified. Contact: za1404491@student.qu.edu.qa, zumin@qu.edu.qa, almansouri@qu.edu.qa, h.alkhatib@qu.edu.qa, aaja@qu.edu.qa, abdshaito@qu.edu.qa, jessica.saliba@balamand.edu.lb, jamilnidal@gmail.com.
This PaperVitamin DAll
Association between lifestyle factors and COVID-19: findings from Qatar Biobank
Zoha Akbar, Hasna H Kunhipurayil, Jessica Saliba, Jamil Ahmad, Layla Al-Mansoori, Hebah A Al-Khatib, Asmaa A Al Thani, Zumin Shi, Abdullah A Shaito
doi:10.20944/preprints202311.0330.v1
Coronavirus Disease 2019 (COVID-19) exhibits a significant variation in presentation of symptoms ranging from mild to severe life-threatening symptoms, including death. COVID-19 infection susceptibility has been linked with various covariates, but studies in Qatar are limited. Data from Qatar Biobank (QBB) (n = 10,000; 18-to 79-year-old adults) were analyzed for associations between sociodemographic and lifestyle factors and susceptibility to COVID-19. Logistic regression was used to assess the associations between COVID-19 and age, gender, body mass index (BMI), smoking status, education level, dietary patterns, supplement use, physical activity, history of bariatric surgery, diabetes, and hypertension. In total, 10.5% (n = 1045) of the participants had COVID-19. Compared to non-smokers, current and ex-smokers had lower odds of having COVID-19 (odds ratio [OR]= 0.55; 95% CI: 0.44-0.68 and OR= 0.70; 95% CI: 0.57-0.86, respectively). Vitamin D supplement use was associated with an 18% reduction of the likelihood of contracting COVID-19 (OR = 0.82; 95% CI: 0.69-0.97). Obesity (BMI ≥30 kg/m 2 ), history of bariatric surgery and higher adherence to the modern dietary pattern-characterized by consumption of foods high in saturated fat and refined carbohydrates-were positively associated with COVID-19. Our findings indicate that adopting a healthy lifestyle may be helpful in the prevention of COVID-19 infection.
Author Contributions: Conceptualization, A.A.S. and Z.S.; investigation, A.A.S., Z.S., Z.A., J.S.; resources, A.A.S., Z.S.; writing-original draft preparation, A.A.S., Z.S., Z.A., ; writing-review and editing, All Authors; Supervision, A.A.S., Z.S., A.A.A.T; project administration, A.A.S.; funding acquisition, A.A.S. All authors have read and agreed to the published version of the manuscript. Funding: Qatar National Research Fund (QNRF) grant number RRC02-0807-210,022 to A.A.S. The funding source (QNRF) had no role in study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit the article for publication. Institutional Review Board
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