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The influence of physical activity level on the length of stay in hospital in older men survivors of COVID-19

Antunes et al., Sport Sciences for Health, doi:10.1007/s11332-022-00948-7
Jun 2022  
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ICU admission 80% Improvement Relative Risk CT >50% 40% CT 25-50% 73% Hospitalization time 43% Disease duration 26% Exercise for COVID-19  Antunes et al.  Prophylaxis Does physical activity reduce risk for COVID-19? Retrospective 39 patients in Brazil (September - December 2020) Shorter hospitalization with higher activity levels (p=0.03) c19early.org Antunes et al., Sport Sciences for Hea.., Jun 2022 Favorsexercise Favorsinactivity 0 0.5 1 1.5 2+
Exercise for COVID-19
9th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 68 studies.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 110 treatments. c19early.org
Retrospective 39 hospitalized COVID-19 survivors >60 years old, showing shorter hospitalization for patients with active lifestyles before COVID-19 symptoms.
risk of ICU admission, 80.2% lower, RR 0.20, p = 0.06, high activity levels 1 of 14 (7.1%), low activity levels 9 of 25 (36.0%), NNT 3.5.
risk of miscellaneous, 40.5% lower, RR 0.60, p = 0.48, high activity levels 3 of 14 (21.4%), low activity levels 9 of 25 (36.0%), NNT 6.9, CT abnormalities >50%.
risk of miscellaneous, 72.5% lower, RR 0.27, p = 0.04, high activity levels 2 of 14 (14.3%), low activity levels 13 of 25 (52.0%), NNT 2.7, CT abnormalities 25-50%.
hospitalization time, 43.4% lower, relative time 0.57, p = 0.03, high activity levels 14, low activity levels 25.
miscellaneous, 25.5% lower, relative time 0.74, p = 0.02, high activity levels 14, low activity levels 25.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Antunes et al., 11 Jun 2022, retrospective, Brazil, peer-reviewed, survey, 5 authors, study period September 2020 - December 2020. Contact: antunes.edher@gmail.com.
This PaperExerciseAll
The influence of physical activity level on the length of stay in hospital in older men survivors of COVID-19
E L Antunes, B M Costa, R C Sochodolak, L M Vargas, N M Okuno
Sport Sciences for Health, doi:10.1007/s11332-022-00948-7
The purpose of this study was to verify the influence of physical activity level on the length of hospital stay in older men recovered from COVID-19. In total, 126 older men diagnosed with COVID-19 were admitted to the hospital between September and December 2020. Among them, 70 survived, of which 39 older men were included in the study. Within 30 days after discharge, patients answered the International Physical Activity Questionnaire to measure their physical activity level through phone contact, with questions corresponding to the week before symptom onset. Clinical and laboratorial data from admission, days between onset of symptoms and admission, length of stay, computed tomography abnormalities, and the need for the intensive care unit were collected. The groups (active × sedentary) were compared using the Student t test or Mann-Whitney test for quantitative data and chi-square test was used for categorical data. There is no difference between the groups in characteristics of admission (p > 0.05), except by potassium level. Active older men had a shorter length of stay (6.50 ± 3.46 vs 11.48 ± 7.63 days; p = 0.03), disease duration (15.71 ± 4.84 vs 21.09 ± 7.69 days; p = 0.02), and lower frequency of lung damage when compared to their sedentary counterparts. In conclusion, being physically active prior to infection can attenuate length of hospital stay in older men with COVID-19.
Declarations Conflict of interest The authors report no conflict of interest. Ethical approval This study was conducted in accordance with the recommendations from the Declaration of Helsinki. Informed consent All participants provided informed consent prior to their participation. Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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J Med Virol ' '93:250–256', 'journal-title': 'J Med Virol'}, { 'key': '948_CR54', 'doi-asserted-by': 'publisher', 'author': 'FE Marino', 'year': '2021', 'unstructured': 'Marino FE, Vargas NT, Skein M et al (2021) Metabolic and inflammatory ' 'health in SARS-CoV-2 and the potential role for habitual exercise in ' 'reducing disease severity. Inflamm Res. ' 'https://doi.org/10.1007/s00011-021-01517-3', 'journal-title': 'Inflamm Res', 'DOI': '10.1007/s00011-021-01517-3'}, { 'key': '948_CR55', 'doi-asserted-by': 'publisher', 'first-page': '1', 'DOI': '10.12820/rbafs.25e0113', 'volume': '25', 'author': 'TS Matias', 'year': '2020', 'unstructured': 'Matias TS, Dominski FH (2020) The COVID-19 pandemic challenges physical ' 'activity with two emerging paradigms. 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BMC Med Res Methodol 18:1–12', 'journal-title': 'BMC Med Res Methodol'}, { 'key': '948_CR58', 'first-page': '1', 'volume': '17', 'author': 'A Castañeda-Babarro', 'year': '2021', 'unstructured': 'Castañeda-Babarro A, Arbillaga-Etxarri A, Gutiérrez-Santamaría B et al ' '(2021) Physical activity change during COVID-19 confinement. Int J ' 'Environ Res Public Health 17:1–10', 'journal-title': 'Int J Environ Res Public Health'}], 'container-title': 'Sport Sciences for Health', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://link.springer.com/content/pdf/10.1007/s11332-022-00948-7.pdf', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://link.springer.com/article/10.1007/s11332-022-00948-7/fulltext.html', 'content-type': 'text/html', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://link.springer.com/content/pdf/10.1007/s11332-022-00948-7.pdf', 'content-type': 'application/pdf', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2022, 6, 11]], 'date-time': '2022-06-11T08:09:43Z', 'timestamp': 1654934983000}, 'score': 1, 'resource': {'primary': {'URL': 'https://link.springer.com/10.1007/s11332-022-00948-7'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2022, 6, 11]]}, 'references-count': 58, 'alternative-id': ['948'], 'URL': 'http://dx.doi.org/10.1007/s11332-022-00948-7', 'relation': {}, 'ISSN': ['1824-7490', '1825-1234'], 'subject': ['Orthopedics and Sports Medicine'], 'container-title-short': 'Sport Sci Health', 'published': {'date-parts': [[2022, 6, 11]]}, 'assertion': [ { 'value': '10 September 2021', 'order': 1, 'name': 'received', 'label': 'Received', 'group': {'name': 'ArticleHistory', 'label': 'Article History'}}, { 'value': '6 April 2022', 'order': 2, 'name': 'accepted', 'label': 'Accepted', 'group': {'name': 'ArticleHistory', 'label': 'Article History'}}, { 'value': '11 June 2022', 'order': 3, 'name': 'first_online', 'label': 'First Online', 'group': {'name': 'ArticleHistory', 'label': 'Article History'}}, {'order': 1, 'name': 'Ethics', 'group': {'name': 'EthicsHeading', 'label': 'Declarations'}}, { 'value': 'The authors report no conflict of interest.', 'order': 2, 'name': 'Ethics', 'group': {'name': 'EthicsHeading', 'label': 'Conflict of interest'}}, { 'value': 'This study was conducted in accordance with the recommendations from the ' 'Declaration of Helsinki.', 'order': 3, 'name': 'Ethics', 'group': {'name': 'EthicsHeading', 'label': 'Ethical approval'}}, { 'value': 'All participants provided informed consent prior to their participation.', 'order': 4, 'name': 'Ethics', 'group': {'name': 'EthicsHeading', 'label': 'Informed consent'}}, { 'value': 'This content has been made available to all.', 'name': 'free', 'label': 'Free to read'}]}
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