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Potential of turmeric-derived compounds against RNA-dependent RNA polymerase of SARS-CoV-2: An in-silico approach

Singh et al., Computers in Biology and Medicine, doi:10.1016/j.compbiomed.2021.104965
Oct 2021  
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In Silico study showing strong binding affinity of curcumin and diacetylcurcumin with SARS-CoV-2 RNA-dependent RNA polymerase. Comparison with remdesivir and favipiravir suggested greater potential of these compounds as an RdRp inhibitor.
Singh et al., 22 Oct 2021, peer-reviewed, 3 authors.
In Silico studies are an important part of preclinical research, however results may be very different in vivo.
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Potential of turmeric-derived compounds against RNA‐dependent RNA polymerase of SARS‐CoV‐2: An in-silico approach
Rahul Singh, Vijay Kumar Bhardwaj, Rituraj Purohit
Computers in Biology and Medicine, doi:10.1016/j.compbiomed.2021.104965
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Competing interests All authors hereby declare that they have no competing interests related to this work. J o u r n a l P r e -p r o o f
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