In vitro antiviral activity against SARS‐CoV ‐2 of common herbal medicinal extracts and their bioactive compounds
Kristi Leka, Carla Hamann, Pauline Desdemoustier, Michel Frédérich, Mutien‐marie Garigliany, Allison Ledoux
Phytotherapy Research, doi:10.1002/ptr.7463
To the Editor, The coronavirus SARS-CoV-2 spread all around the world, leading to an unprecedented pandemic. Up to date, some effective treatments have been highlighted to treat the symptoms, but not to cure the COVID-19 disease. At least, some well-known medicines have been proposed, but have rapidly become the subject of some controversy, such as hydroxychloroquine combined or not azithromycin
FUNDING INFORMATION Fonds Léon Fredericq, Grant/Award Number: 2020-2021 -113 -Sub. F/E; Fondation Hospitalo Universitaire Léon Fredericq.
CONFLICT OF INTEREST The authors declare no conflicts of interest.
References
Derosa, Maffioli, D'angelo, Di Pierro, A role for quercetin in coronavirus disease 2019 (COVID-19), Phytotherapy Research,
doi:10.1002/ptr.6887Ledoux, Leka, Bonnet, Blanquer, Alembert et al., In vitro antiviral activity against SARS-CoV-2 of 28 Strychnos extracts, Phytotherapy Research,
doi:10.1002/ptr.7394Maisonnasse, Guedj, Contreras, Behillil, Solas et al., Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates, Nature,
doi:10.1038/s41586-020-2558-4Okour, Al-Kofahi, Austin, Hydroxychloroquine and azithromycin as potential treatments for COVID-19; clinical status impacts the outcome, Journal of Pharmacokinetics and Pharmacodynamics,
doi:10.1007/s10928-020-09689-xSaber-Moghaddam, Salari, Hejazi, Amini, Taherzadeh et al., Oral nano-curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease-19 patients: An open label nonrandomized clinical trial, Phytotherapy Research,
doi:10.1002/ptr.7004Soni, Mehta, Ratre, Tiwari, Amit et al., Curcumin, a traditional spice component, can hold the promise against COVID-19?, European Journal of Pharmacology,
doi:10.1016/j.ejphar.2020.173551Tutunchi, Naeini, Ostadrahimi, Hosseinzadeh-Attar, Naringenin, a flavanone with antiviral and anti-inflammatory effects: A promising treatment strategy against COVID-19, Phytotherapy Research,
doi:10.1002/ptr.6781Zahedipour, Hosseini, Sathyapalan, Majeed, Jamialahmadi et al., Potential effects of curcumin in the treatment of COVID-19 infection, Phytotherapy Research,
doi:10.1002/ptr.6738Zaidi, Dehgani-Mobaraki, The mechanisms of action of ivermectin against SARS-CoV-2-An extensive review, The Journal of Antibiotics,
doi:10.1038/s41429-021-00491-6DOI record:
{
"DOI": "10.1002/ptr.7463",
"ISSN": [
"0951-418X",
"1099-1573"
],
"URL": "http://dx.doi.org/10.1002/ptr.7463",
"alternative-id": [
"10.1002/ptr.7463"
],
"archive": [
"Portico"
],
"assertion": [
{
"group": {
"label": "Publication History",
"name": "publication_history"
},
"label": "Received",
"name": "received",
"order": 0,
"value": "2022-02-14"
},
{
"group": {
"label": "Publication History",
"name": "publication_history"
},
"label": "Accepted",
"name": "accepted",
"order": 1,
"value": "2022-03-25"
},
{
"group": {
"label": "Publication History",
"name": "publication_history"
},
"label": "Published",
"name": "published",
"order": 2,
"value": "2022-04-09"
}
],
"author": [
{
"affiliation": [
{
"name": "Laboratory of Pharmacognosy, Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
},
{
"name": "Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
},
{
"name": "Laboratory of Veterinary Pathology, Fundamental and Applied Research for Animals & Health (FARAH) University of Liège Liège Belgium"
}
],
"family": "Leka",
"given": "Kristi",
"sequence": "first"
},
{
"affiliation": [
{
"name": "Laboratory of Pharmacognosy, Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
}
],
"family": "Hamann",
"given": "Carla",
"sequence": "additional"
},
{
"affiliation": [
{
"name": "Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
}
],
"family": "Desdemoustier",
"given": "Pauline",
"sequence": "additional"
},
{
"affiliation": [
{
"name": "Laboratory of Pharmacognosy, Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
}
],
"family": "Frédérich",
"given": "Michel",
"sequence": "additional"
},
{
"affiliation": [
{
"name": "Laboratory of Veterinary Pathology, Fundamental and Applied Research for Animals & Health (FARAH) University of Liège Liège Belgium"
}
],
"family": "Garigliany",
"given": "Mutien‐Marie",
"sequence": "additional"
},
{
"ORCID": "http://orcid.org/0000-0002-4052-6336",
"affiliation": [
{
"name": "Laboratory of Pharmacognosy, Center of Interdisciplinary Research on Medicines (CIRM) University of Liège Liège Belgium"
}
],
"authenticated-orcid": false,
"family": "Ledoux",
"given": "Allison",
"sequence": "additional"
}
],
"container-title": [
"Phytotherapy Research"
],
"content-domain": {
"crossmark-restriction": true,
"domain": [
"onlinelibrary.wiley.com"
]
},
"created": {
"date-parts": [
[
2022,
4,
9
]
],
"date-time": "2022-04-09T09:04:03Z",
"timestamp": 1649495043000
},
"deposited": {
"date-parts": [
[
2022,
4,
9
]
],
"date-time": "2022-04-09T09:04:07Z",
"timestamp": 1649495047000
},
"funder": [
{
"DOI": "10.13039/501100006673",
"award": [
"2020‐2021 ‐ 113 ‐ Sub. F/E"
],
"doi-asserted-by": "publisher",
"name": "Fonds Léon Fredericq"
}
],
"indexed": {
"date-parts": [
[
2022,
4,
9
]
],
"date-time": "2022-04-09T09:42:09Z",
"timestamp": 1649497329250
},
"is-referenced-by-count": 0,
"issn-type": [
{
"type": "print",
"value": "0951-418X"
},
{
"type": "electronic",
"value": "1099-1573"
}
],
"issued": {
"date-parts": [
[
2022,
4,
9
]
]
},
"language": "en",
"license": [
{
"URL": "http://onlinelibrary.wiley.com/termsAndConditions#vor",
"content-version": "vor",
"delay-in-days": 0,
"start": {
"date-parts": [
[
2022,
4,
9
]
],
"date-time": "2022-04-09T00:00:00Z",
"timestamp": 1649462400000
}
},
{
"URL": "http://doi.wiley.com/10.1002/tdm_license_1.1",
"content-version": "tdm",
"delay-in-days": 0,
"start": {
"date-parts": [
[
2022,
4,
9
]
],
"date-time": "2022-04-09T00:00:00Z",
"timestamp": 1649462400000
}
}
],
"link": [
{
"URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7463",
"content-type": "application/pdf",
"content-version": "vor",
"intended-application": "text-mining"
},
{
"URL": "https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ptr.7463",
"content-type": "application/xml",
"content-version": "vor",
"intended-application": "text-mining"
},
{
"URL": "https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7463",
"content-type": "unspecified",
"content-version": "vor",
"intended-application": "similarity-checking"
}
],
"member": "311",
"original-title": [],
"prefix": "10.1002",
"published": {
"date-parts": [
[
2022,
4,
9
]
]
},
"published-online": {
"date-parts": [
[
2022,
4,
9
]
]
},
"publisher": "Wiley",
"reference": [
{
"DOI": "10.1002/ptr.6887",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_2_1"
},
{
"DOI": "10.1016/S1473-3099(21)00768-4",
"article-title": "Transmissibility of SARS‐CoV‐2 among fully vaccinated individuals",
"author": "Franco‐Paredes C.",
"doi-asserted-by": "crossref",
"first-page": "16",
"issue": "1",
"journal-title": "The Lancet Infectious Diseases",
"key": "e_1_2_1_6_3_1",
"volume": "22",
"year": "2022"
},
{
"DOI": "10.1002/ptr.7394",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_4_1"
},
{
"DOI": "10.1038/s41586-020-2558-4",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_5_1"
},
{
"DOI": "10.1007/s10928-020-09689-x",
"article-title": "Hydroxychloroquine and azithromycin as potential treatments for COVID‐19; clinical status impacts the outcome",
"author": "Okour M.",
"doi-asserted-by": "crossref",
"first-page": "187",
"journal-title": "Journal of Pharmacokinetics and Pharmacodynamics",
"key": "e_1_2_1_6_6_1",
"volume": "47",
"year": "2020"
},
{
"DOI": "10.1002/ptr.7004",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_7_1"
},
{
"DOI": "10.1016/j.ejphar.2020.173551",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_8_1"
},
{
"DOI": "10.1002/ptr.6781",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_9_1"
},
{
"DOI": "10.1002/ptr.6738",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_10_1"
},
{
"DOI": "10.1038/s41429-021-00491-6",
"doi-asserted-by": "publisher",
"key": "e_1_2_1_6_11_1"
}
],
"reference-count": 10,
"references-count": 10,
"relation": {},
"resource": {
"primary": {
"URL": "https://onlinelibrary.wiley.com/doi/10.1002/ptr.7463"
}
},
"score": 1,
"short-container-title": [
"Phytotherapy Research"
],
"short-title": [],
"source": "Crossref",
"subject": [
"Pharmacology"
],
"subtitle": [],
"title": [
"In vitro antiviral activity against\n <scp>SARS‐CoV</scp>\n ‐2 of common herbal medicinal extracts and their bioactive compounds"
],
"type": "journal-article",
"update-policy": "http://dx.doi.org/10.1002/crossmark_policy"
}
