COVID-19 and Vitamin D (Co-VIVID Study): a systematic review and meta-analysis of randomized controlled trials

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WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data n.d. https://covid19.who.int/ (accessed August 6, 2021)." }, { "DOI": "10.1016/j.exger.2021.111507", "doi-asserted-by": "crossref", "key": "cit0002", "unstructured": "2. Farshbafnadi M, Kamali Zonouzi S, Sabahi M, Dolatshahi M, Aarabi MH. Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors. Exp Gerontol. 2021;154:111507." }, { "DOI": "10.1139/cjpp-2014-0352", "doi-asserted-by": "crossref", "key": "cit0003", "unstructured": "3. Watkins RR, Lemonovich TL, Salata RA. An update on the association of vitamin D deficiency with common infectious diseases. Can J Physiol Pharmacol. 2015;93(5):363-8." }, { "DOI": "10.1016/j.nut.2021.111356", "doi-asserted-by": "crossref", "key": "cit0004", "unstructured": "4. Brito DTM, Ribeiro LHC, Daltro CHDC, Silva RB. The possible benefits of vitamin D in COVID-19. Nutrition. 2021;91-92:111356." }, { "DOI": "10.3390/biomedicines8050129", "doi-asserted-by": "crossref", "key": "cit0005", "unstructured": "5. Glinsky GV. Tripartite Combination of Candidate Pandemic Mitigation Agents: Vitamin D, Quercetin, and Estradiol Manifest Properties of Medicinal Agents for Targeted Mitigation of the COVID-19 Pandemic Defined by Genomics-Guided Tracing of SARS-CoV-2 Targets in Human Cells. Biomedicines. 2020;8(5):129." }, { "DOI": "10.3390/nu9070651", "doi-asserted-by": "crossref", "key": "cit0006", "unstructured": "6. Gois PHF, Ferreira D, Olenski S, Seguro AC. Vitamin D and Infectious Diseases: Simple Bystander or Contributing Factor? Nutrients. 2017;9(7):651." }, { "DOI": "10.3390/nu13051714", "doi-asserted-by": "crossref", "key": "cit0007", "unstructured": "7. AlSafar H, Grant WB, Hijazi R, Uddin M, Alkaabi N, Tay G, et al. COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents. Nutrients. 2021;13(5):1714." }, { "DOI": "10.1002/rmv.2119", "doi-asserted-by": "crossref", "key": "cit0008", "unstructured": "8. Malek Mahdavi A. A brief review of interplay between vitamin D and angiotensin-converting enzyme 2: Implications for a potential treatment for COVID-19. Rev Med Virol. 2020;30(5):e2119." }, { "DOI": "10.2217/imt-2020-0349", "doi-asserted-by": "crossref", "key": "cit0009", "unstructured": "9. Pinheiro MM, Fabbri A, Infante M. Cytokine storm modulation in COVID-19: a proposed role for vitamin D and DPP-4 inhibitor combination therapy (VIDPP-4i). Immunotherapy. 2021;13(9):753-65." }, { "DOI": "10.1126/science.abb8923", "doi-asserted-by": "crossref", "key": "cit0010", "unstructured": "10. Graham BS. Rapid COVID-19 vaccine development. Science. 2020;368(6494):945-6." }, { "DOI": "10.1515/cclm-2020-1567", "doi-asserted-by": "crossref", "key": "cit0011", "unstructured": "11. Orchard L, Baldry M, Nasim-Mohi M, et al. Vitamin-D levels and intensive care unit outcomes of a cohort of critically ill COVID-19 patients. Clin Chem Lab Med. 2021;59(6):1155-63." }, { "DOI": "10.1016/j.mayocp.2021.01.001", "doi-asserted-by": "crossref", "key": "cit0012", "unstructured": "12. Angelidi AM, Belanger MJ, Lorinsky MK, et al. Vitamin D Status Is Associated With In-Hospital Mortality and Mechanical Ventilation: A Cohort of COVID-19 Hospitalized Patients. Mayo Clin Proc. 2021;96(4):875-86." }, { "DOI": "10.1093/jn/nxab107", "doi-asserted-by": "crossref", "key": "cit0013", "unstructured": "13. Bychinin MV, Klypa TV, Mandel IA, et al. Low Circulating Vitamin D in Intensive Care Unit-Admitted COVID-19 Patients as a Predictor of Negative Outcomes. J Nutr. 2021;151(8):2199-205." }, { "DOI": "10.1080/07315724.2021.1877580", "doi-asserted-by": "crossref", "key": "cit0014", "unstructured": "14. Infante M, Buoso A, Pieri M, et al. Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study. J Am Coll Nutr. 2021. doi: 10.1080/07315724.2021.1877580." }, { "key": "cit0015", "unstructured": "15. Infante M, Pieri M, Lupisella S, et al. Low testosterone levels and high estradiol to testosterone ratio are associated with hyperinflammatory state and mortality in hospitalized men with COVID-19. Eur Rev Med Pharmacol Sci. 2021;25(19):5889-903." }, { "DOI": "10.1186/s12879-021-06281-7", "doi-asserted-by": "crossref", "key": "cit0016", "unstructured": "16. Campi I, Gennari L, Merlotti D, et al. Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy. BMC Infect Dis. 2021;21(1):566." }, { "DOI": "10.3390/nu12113361", "doi-asserted-by": "crossref", "key": "cit0017", "unstructured": "17. Mercola J, Grant WB, Wagner CL. Evidence Regarding Vitamin D and Risk of COVID-19 and Its Severity. Nutrients. 2020;12(11):3361." }, { "DOI": "10.1016/j.jsbmb.2021.105883", "doi-asserted-by": "crossref", "key": "cit0018", "unstructured": "18. Petrelli F, Luciani A, Perego G, Dognini G, Colombelli PL, Ghidini A. Therapeutic and prognostic role of vitamin D for COVID-19 infection: A systematic review and meta-analysis of 43 observational studies. J Steroid Biochem Mol Biol. 2021;211:105883." }, { "key": "cit0019", "unstructured": "19. Velikova T, Fabbri A, Infante M. The role of vitamin D as a potential adjuvant for COVID-19 vaccines. Eur Rev Med Pharmacol Sci. 2021;25(17):5323-7." }, { "DOI": "10.3390/ijms22168988", "doi-asserted-by": "crossref", "key": "cit0020", "unstructured": "20. Chiu SK, Tsai KW, Wu CC, et al. Putative Role of Vitamin D for COVID-19 Vaccination. Int J Mol Sci. 2021;22(16):8988." }, { "DOI": "10.1016/j.jsbmb.2020.105751", "doi-asserted-by": "crossref", "key": "cit0021", "unstructured": "21. Castillo EM, Entrenas Costa LM, Vaquero Barrios JM, et al. “Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study”. J Steroid Biochem Mol Biol. 2020;203:105751." }, { "DOI": "10.1038/s41598-021-90189-4", "doi-asserted-by": "crossref", "key": "cit0022", "unstructured": "22. Lakkireddy M, Gadiga SG, Malathi RD, et al. Impact of daily high dose oral vitamin D therapy on the inflammatory markers in patients with COVID 19 disease. Sci Rep. 2021;11(1):10641." }, { "DOI": "10.1001/jama.2020.26848", "doi-asserted-by": "crossref", "key": "cit0023", "unstructured": "23. Murai IH, Fernandes AL, Sales LP, et al. Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial. JAMA. 2021;325(11):1053-1060." }, { "DOI": "10.1136/postgradmedj-2020-139065", "doi-asserted-by": "crossref", "key": "cit0024", "unstructured": "24. Rastogi A, Bhansali A, Khare N, et al. Short term, high-dose vitamin D supplementation for COVID-19 disease: a randomised, placebo-controlled, study (SHADE study). Postgrad Med J. 2020:postgradmedj-2020-139065. doi: 10.1136/postgradmedj-2020-139065.25. Sabico S, Enani MA, Sheshah E, et al. Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial. Nutrients. 2021;13(7):2170." }, { "DOI": "10.3390/jcm10112378", "doi-asserted-by": "crossref", "key": "cit0025", "unstructured": "26. Sánchez-Zuno GA, González-Estevez G, Matuz-Flores MG, et al. Vitamin D Levels in COVID-19 Outpatients from Western Mexico: Clinical Correlation and Effect of Its Supplementation. J Clin Med. 2021;10:2378." }, { "DOI": "10.1371/journal.pmed.1000097", "doi-asserted-by": "crossref", "key": "cit0026", "unstructured": "27. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097." }, { "DOI": "10.1136/bmj.l4898", "doi-asserted-by": "crossref", "key": "cit0027", "unstructured": "28. Sterne JAC, Savović J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898." }, { "DOI": "10.1093/ije/dys041", "doi-asserted-by": "crossref", "key": "cit0028", "unstructured": "29. Turner RM, Davey J, Clarke MJ, Thompson SG, Higgins JP. Predicting the extent of heterogeneity in meta-analysis, using empirical data from the Cochrane Database of Systematic Reviews. Int J Epidemiol. 2012;41(3):818-27." }, { "DOI": "10.1002/rmv.2032", "doi-asserted-by": "crossref", "key": "cit0029", "unstructured": "30. Teymoori-Rad M, Shokri F, Salimi V, Marashi SM. The interplay between vitamin D and viral infections. Rev Med Virol. 2019;29(2):e2032." }, { "DOI": "10.1136/thorax-2020-BTSabstracts.105", "doi-asserted-by": "crossref", "key": "cit0030", "unstructured": "31. Jolliffe DA, Camargo CA Jr, Sluyter JD, et al. Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials. Lancet Diabetes Endocrinol. 2021;9(5):276-292." }, { "DOI": "10.1016/S2213-8587(21)00075-9", "doi-asserted-by": "crossref", "key": "cit0031", "unstructured": "32. Lips P. Vitamin D to prevent acute respiratory infections. Lancet Diabetes Endocrinol. 2021;9(5):249-251." }, { "DOI": "10.1007/s10787-021-00835-6", "doi-asserted-by": "crossref", "key": "cit0032", "unstructured": "33. Menshawey E, Menshawey R, Nabeh OA. Shedding light on vitamin D: the shared mechanistic and pathophysiological role between hypovitaminosis D and COVID-19 risk factors and complications. Inflammopharmacology. 2021;29(4):1017-1031." }, { "DOI": "10.1016/j.virusres.2020.198235", "doi-asserted-by": "crossref", "key": "cit0033", "unstructured": "34. Kumar R, Rathi H, Haq A, Wimalawansa SJ, Sharma A. Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19. Virus Res. 2021;292:198235." }, { "DOI": "10.1007/s40520-021-01894-z", "doi-asserted-by": "crossref", "key": "cit0034", "unstructured": "35. Raisi-Estabragh Z, Martineau AR, Curtis EM, et al. Vitamin D and coronavirus disease 2019 (COVID-19): rapid evidence review. 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