The role of vitamin D in the prevention and treatment of SARS-CoV-2 infection: A meta-analysis of randomized controlled trials

{ 'indexed': {'date-parts': [[2023, 10, 7]], 'date-time': '2023-10-07T04:48:11Z', 'timestamp': 1696654091421}, 'reference-count': 54, 'publisher': 'Elsevier BV', 'issue': '11', 'license': [ { 'start': { 'date-parts': [[2023, 11, 1]], 'date-time': '2023-11-01T00:00:00Z', 'timestamp': 1698796800000}, 'content-version': 'tdm', 'delay-in-days': 0, 'URL': 'https://www.elsevier.com/tdm/userlicense/1.0/'}, { 'start': { 'date-parts': [[2023, 9, 19]], 'date-time': '2023-09-19T00:00:00Z', 'timestamp': 1695081600000}, 'content-version': 'vor', 'delay-in-days': 0, 'URL': 'http://creativecommons.org/licenses/by-nc-nd/4.0/'}], 'content-domain': { 'domain': [ 'clinicalkey.fr', 'clinicalkey.jp', 'clinicalkey.es', 'clinicalkey.com.au', 'clinicalkey.com', 'clinicalnutritionjournal.com', 'elsevier.com', 'sciencedirect.com'], 'crossmark-restriction': True}, 'published-print': {'date-parts': [[2023, 11]]}, 'DOI': '10.1016/j.clnu.2023.09.008', 'type': 'journal-article', 'created': {'date-parts': [[2023, 9, 20]], 'date-time': '2023-09-20T15:35:52Z', 'timestamp': 1695224152000}, 'page': '2198-2206', 'update-policy': 'http://dx.doi.org/10.1016/elsevier_cm_policy', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'The role of vitamin D in the prevention and treatment of SARS-CoV-2 infection: A meta-analysis ' 'of randomized controlled trials', 'prefix': '10.1016', 'volume': '42', 'author': [ {'given': 'Jiahao', 'family': 'Meng', 'sequence': 'first', 'affiliation': []}, {'given': 'Xi', 'family': 'Li', 'sequence': 'additional', 'affiliation': []}, {'given': 'Weijie', 'family': 'Liu', 'sequence': 'additional', 'affiliation': []}, {'given': 'Yifan', 'family': 'Xiao', 'sequence': 'additional', 'affiliation': []}, {'given': 'Hang', 'family': 'Tang', 'sequence': 'additional', 'affiliation': []}, {'given': 'Yumei', 'family': 'Wu', 'sequence': 'additional', 'affiliation': []}, {'given': 'Yilin', 'family': 'Xiong', 'sequence': 'additional', 'affiliation': []}, { 'ORCID': 'http://orcid.org/0000-0003-1135-7876', 'authenticated-orcid': False, 'given': 'Shuguang', 'family': 'Gao', 'sequence': 'additional', 'affiliation': []}], 'member': '78', 'reference': [ { 'issue': '25', 'key': '10.1016/j.clnu.2023.09.008_bib1', 'doi-asserted-by': 'crossref', 'first-page': '2451', 'DOI': '10.1056/NEJMcp2009575', 'article-title': 'Severe covid-19', 'volume': '383', 'author': 'Berlin', 'year': '2020', 'journal-title': 'N\xa0Engl J Med'}, { 'key': '10.1016/j.clnu.2023.09.008_bib2', 'doi-asserted-by': 'crossref', 'first-page': 'n436', 'DOI': '10.1136/bmj.n436', 'article-title': 'Severe covid-19 pneumonia: pathogenesis and clinical management', 'volume': '372', 'author': 'Attaway', 'year': '2021', 'journal-title': 'BMJ'}, { 'issue': '7', 'key': '10.1016/j.clnu.2023.09.008_bib3', 'doi-asserted-by': 'crossref', 'first-page': '2097', 'DOI': '10.3390/nu12072097', 'article-title': 'Immunologic effects of vitamin D on human health and disease', 'volume': '12', 'author': 'Charoenngam', 'year': '2020', 'journal-title': 'Nutrients'}, { 'issue': '17', 'key': '10.1016/j.clnu.2023.09.008_bib4', 'doi-asserted-by': 'crossref', 'first-page': '9784', 'DOI': '10.3390/ijms23179784', 'article-title': 'An update on the effects of vitamin D on the immune system and ' 'autoimmune diseases', 'volume': '23', 'author': 'S√ģrbe', 'year': '2022', 'journal-title': 'Int J Mol Sci'}, { 'issue': '4', 'key': '10.1016/j.clnu.2023.09.008_bib5', 'doi-asserted-by': 'crossref', 'first-page': '604', 'DOI': '10.1111/joim.13536', 'article-title': 'Vitamin D and COVID-19-revisited', 'volume': '292', 'author': 'Subramanian', 'year': '2022', 'journal-title': 'J\xa0Intern Med'}, { 'issue': '6', 'key': '10.1016/j.clnu.2023.09.008_bib6', 'doi-asserted-by': 'crossref', 'first-page': '4240', 'DOI': '10.3390/nu7064240', 'article-title': 'Modulation of the immune response to respiratory viruses by vitamin D', 'volume': '7', 'author': 'Greiller', 'year': '2015', 'journal-title': 'Nutrients'}, { 'key': '10.1016/j.clnu.2023.09.008_bib7', 'doi-asserted-by': 'crossref', 'first-page': '321', 'DOI': '10.1016/j.jsbmb.2012.11.017', 'article-title': 'Vitamin D in the prevention of acute respiratory infection: systematic ' 'review of clinical studies', 'volume': '136', 'author': 'Jolliffe', 'year': '2013', 'journal-title': 'J\xa0Steroid Biochem Mol Biol'}, { 'issue': '17', 'key': '10.1016/j.clnu.2023.09.008_bib8', 'doi-asserted-by': 'crossref', 'first-page': '3020', 'DOI': '10.3390/ijerph16173020', 'article-title': 'Acute respiratory tract infection and 25-hydroxyvitamin D ' 'concentration: a systematic review and meta-analysis', 'volume': '16', 'author': 'Pham', 'year': '2019', 'journal-title': 'Int J Environ Res Publ Health'}, { 'issue': '10', 'key': '10.1016/j.clnu.2023.09.008_bib9', 'doi-asserted-by': 'crossref', 'first-page': 'e1106', 'DOI': '10.1210/clinem/dgad207', 'article-title': 'Low vitamin D levels are associated with Long COVID syndrome in ' 'COVID-19 survivors', 'volume': '108', 'author': 'di Filippo', 'year': '2023', 'journal-title': 'J\xa0Clin Endocrinol Metabol'}, { 'issue': '10', 'key': '10.1016/j.clnu.2023.09.008_bib10', 'doi-asserted-by': 'crossref', 'first-page': '665', 'DOI': '10.1093/qjmed/hcac040', 'article-title': 'Does vitamin D supplementation reduce COVID-19 severity?: a systematic ' 'review', 'volume': '115', 'author': 'Shah', 'year': '2022', 'journal-title': 'QJM : monthly journal of the Association of Physicians'}, { 'key': '10.1016/j.clnu.2023.09.008_bib11', 'doi-asserted-by': 'crossref', 'first-page': '1023903', 'DOI': '10.3389/fimmu.2022.1023903', 'article-title': 'Vitamin D supplementation for the treatment of COVID-19: a systematic ' 'review and meta-analysis of randomized controlled trials', 'volume': '13', 'author': 'Kümmel', 'year': '2022', 'journal-title': 'Front Immunol'}, { 'issue': '7', 'key': '10.1016/j.clnu.2023.09.008_bib12', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pmed.1000097', 'article-title': 'Preferred reporting items for systematic reviews and meta-analyses: the ' 'PRISMA statement', 'volume': '6', 'author': 'Moher', 'year': '2009', 'journal-title': 'PLoS Med'}, { 'key': '10.1016/j.clnu.2023.09.008_bib13', 'doi-asserted-by': 'crossref', 'first-page': 'd5928', 'DOI': '10.1136/bmj.d5928', 'article-title': "The Cochrane Collaboration's tool for assessing risk of bias in " 'randomised trials', 'volume': '343', 'author': 'Higgins', 'year': '2011', 'journal-title': 'Br Med J'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib14', 'doi-asserted-by': 'crossref', 'first-page': '1019', 'DOI': '10.1186/s13063-022-06944-z', 'article-title': 'Oral vitamin D supplemental therapy to attain a desired serum ' '25-hydroxyvitamin D concentration in essential healthcare teams', 'volume': '23', 'author': 'Hosseini', 'year': '2022', 'journal-title': 'Trials'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib15', 'doi-asserted-by': 'crossref', 'first-page': '180', 'DOI': '10.3390/nu15010180', 'article-title': 'Vitamin D3 supplementation at 5000 IU daily for the prevention of ' 'influenza-like illness in healthcare workers: a pragmatic randomized ' 'clinical trial', 'volume': '15', 'author': 'van Helmond', 'year': '2022', 'journal-title': 'Nutrients'}, { 'issue': '4', 'key': '10.1016/j.clnu.2023.09.008_bib16', 'doi-asserted-by': 'crossref', 'first-page': '423', 'DOI': '10.1016/j.arcmed.2022.04.003', 'article-title': 'Efficacy and safety of vitamin D supplementation to prevent COVID-19 in ' 'frontline healthcare workers. A randomized clinical trial', 'volume': '53', 'author': 'Villasis-Keever', 'year': '2022', 'journal-title': 'Arch Med Res'}, { 'key': '10.1016/j.clnu.2023.09.008_bib17', 'article-title': 'Effect of a test-and-treat approach to vitamin D supplementation on ' 'risk of all cause acute respiratory tract infection and covid-19: phase ' '3 randomised controlled trial (CORONAVIT)', 'volume': '378', 'author': 'Jolliffe', 'year': '2022', 'journal-title': 'Br Med J'}, { 'key': '10.1016/j.clnu.2023.09.008_bib18', 'doi-asserted-by': 'crossref', 'first-page': '111899', 'DOI': '10.1016/j.nut.2022.111899', 'article-title': 'REsCue trial: randomized controlled clinical trial with ' 'extended-release calcifediol in symptomatic COVID-19 outpatients', 'volume': '107', 'author': 'Bishop', 'year': '2023', 'journal-title': 'Nutrition'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib19', 'doi-asserted-by': 'crossref', 'first-page': '18604', 'DOI': '10.1038/s41598-022-22045-y', 'article-title': 'Effect of vitamin D3 supplementation on cellular immunity and ' 'inflammatory markers in COVID-19 patients admitted to the ICU', 'volume': '12', 'author': 'Bychinin', 'year': '2022', 'journal-title': 'Sci Rep'}, { 'issue': '15', 'key': '10.1016/j.clnu.2023.09.008_bib20', 'doi-asserted-by': 'crossref', 'first-page': '3048', 'DOI': '10.3390/nu14153048', 'article-title': 'Positive effects of vitamin D supplementation in patients hospitalized ' 'for COVID-19: a randomized, double-blind, placebo-controlled trial', 'volume': '14', 'author': 'De Niet', 'year': '2022', 'journal-title': 'Nutrients'}, { 'issue': '5', 'key': '10.1016/j.clnu.2023.09.008_bib21', 'doi-asserted-by': 'crossref', 'first-page': '1234', 'DOI': '10.3390/nu15051234', 'article-title': 'Vitamin D supplementation and clinical outcomes in severe COVID-19 ' 'patients-randomized controlled trial', 'volume': '15', 'author': 'Domazet Bugarin', 'year': '2023', 'journal-title': 'Nutrients'}, { 'key': '10.1016/j.clnu.2023.09.008_bib22', 'doi-asserted-by': 'crossref', 'first-page': '116175', 'DOI': '10.1016/j.bone.2021.116175', 'article-title': 'A\xa0randomized pilot study using calcitriol in hospitalized COVID-19 ' 'patients', 'volume': '154', 'author': 'Elamir', 'year': '2022', 'journal-title': 'Bone'}, { 'key': '10.1016/j.clnu.2023.09.008_bib23', 'doi-asserted-by': 'crossref', 'first-page': '105751', 'DOI': '10.1016/j.jsbmb.2020.105751', 'article-title': 'Effect of calcifediol treatment and best available therapy versus best ' 'available therapy on intensive care unit admission and mortality among ' 'patients hospitalized for COVID-19: a pilot randomized clinical study', 'volume': '203', 'author': 'Entrenas Castillo', 'year': '2020', 'journal-title': 'J\xa0Steroid Biochem Mol Biol'}, { 'issue': '13', 'key': '10.1016/j.clnu.2023.09.008_bib24', 'doi-asserted-by': 'crossref', 'first-page': '2602', 'DOI': '10.3390/nu14132602', 'article-title': 'Effect of cholecalciferol supplementation on the clinical features and ' 'inflammatory markers in hospitalized COVID-19 patients: a randomized, ' 'open-label, single-center study', 'volume': '14', 'author': 'Karonova', 'year': '2022', 'journal-title': 'Nutrients'}, { 'issue': '12', 'key': '10.1016/j.clnu.2023.09.008_bib25', 'doi-asserted-by': 'crossref', 'first-page': '1242', 'DOI': '10.1016/j.eprac.2021.09.016', 'volume': '27', 'author': 'Maghbooli', 'year': '2021', 'journal-title': 'Endocr Pract : official journal of the American College of ' 'Endocrinology and the American Association of Clinical ' 'Endocrinologists'}, { 'issue': '1156', 'key': '10.1016/j.clnu.2023.09.008_bib26', 'doi-asserted-by': 'crossref', 'first-page': '87', 'DOI': '10.1136/postgradmedj-2020-139065', 'article-title': 'Short term, high-dose vitamin D supplementation for COVID-19 disease: a ' 'randomised, placebo-controlled, study (SHADE study)', 'volume': '98', 'author': 'Rastogi', 'year': '2022', 'journal-title': 'Postgrad Med'}, { 'key': '10.1016/j.clnu.2023.09.008_bib27', 'doi-asserted-by': 'crossref', 'first-page': '1011522', 'DOI': '10.3389/fphar.2022.1011522', 'article-title': 'The effect of Ni gella sativa and vitamin D3 supplementation on the ' 'clinical outcome in COVID-19 patients: a randomized controlled clinical ' 'trial', 'volume': '13', 'author': 'Said', 'year': '2022', 'journal-title': 'Front Pharmacol'}, { 'issue': '11', 'key': '10.1016/j.clnu.2023.09.008_bib28', 'first-page': '2378', 'article-title': 'Vitamin D levels in COVID-19 outpatients from western Mexico: clinical ' 'correlation and effect of its supplementation', 'volume': '10', 'author': 'Sánchez-Zuno', 'year': '2021', 'journal-title': 'J\xa0Clin Med'}, { 'key': '10.1016/j.clnu.2023.09.008_bib29', 'doi-asserted-by': 'crossref', 'first-page': '943529', 'DOI': '10.3389/fped.2022.943529', 'article-title': 'Efficacy and safety of vitamin D supplementation in hospitalized ' 'COVID-19 pediatric patients: a randomized controlled trial', 'volume': '10', 'author': 'Zurita-Cruz', 'year': '2022', 'journal-title': 'Frontiers in pediatrics'}, { 'key': '10.1016/j.clnu.2023.09.008_bib30', 'doi-asserted-by': 'crossref', 'first-page': '863587', 'DOI': '10.3389/fphar.2022.863587', 'article-title': 'Beneficial effect of short-term supplementation of high dose of vitamin ' 'D(3) in hospitalized patients with COVID-19: a multicenter, ' 'single-blinded, prospective randomized pilot clinical trial', 'volume': '13', 'author': 'Cervero', 'year': '2022', 'journal-title': 'Front Pharmacol'}, { 'issue': '7', 'key': '10.1016/j.clnu.2023.09.008_bib31', 'doi-asserted-by': 'crossref', 'first-page': '2170', 'DOI': '10.3390/nu13072170', 'article-title': 'Effects of a 2-week 5000 IU versus 1000 IU vitamin D3 supplementation ' 'on recovery of symptoms in patients with mild to moderate covid-19: a ' 'randomized clinical trial', 'volume': '13', 'author': 'Sabico', 'year': '2021', 'journal-title': 'Nutrients'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib32', 'doi-asserted-by': 'crossref', 'first-page': '123', 'DOI': '10.1186/s13063-023-07114-5', 'article-title': 'Effect of vitamin D supplementation versus placebo on recovery delay ' 'among COVID-19 Tunisian patients: a randomized-controlled clinical ' 'trial', 'volume': '24', 'author': 'Abroug', 'year': '2023', 'journal-title': 'Trials'}, { 'issue': '5', 'key': '10.1016/j.clnu.2023.09.008_bib33', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pmed.1003999', 'article-title': 'High-dose versus standard-dose vitamin D supplementation in older ' 'adults with COVID-19 (COVIT-TRIAL): a multicenter, open-label, ' 'randomized controlled superiority trial', 'volume': '19', 'author': 'Annweiler', 'year': '2022', 'journal-title': 'PLoS Med'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib34', 'doi-asserted-by': 'crossref', 'first-page': '83', 'DOI': '10.1186/s12916-022-02290-8', 'article-title': 'A\xa0single-oral bolus of 100,000 IU of cholecalciferol at hospital ' 'admission did not improve outcomes in the COVID-19 disease: the ' 'COVID-VIT-D-a randomised multicentre international clinical trial', 'volume': '20', 'author': 'Cannata-Andía', 'year': '2022', 'journal-title': 'BMC Med'}, { 'issue': '5', 'key': '10.1016/j.clnu.2023.09.008_bib35', 'doi-asserted-by': 'crossref', 'DOI': '10.1371/journal.pone.0267918', 'article-title': 'High-dose vitamin D versus placebo to prevent complications in COVID-19 ' 'patients: multicentre randomized controlled clinical trial', 'volume': '17', 'author': 'Mariani', 'year': '2022', 'journal-title': 'PLoS One'}, { 'key': '10.1016/j.clnu.2023.09.008_bib36', 'doi-asserted-by': 'crossref', 'first-page': 'e3549', 'DOI': '10.6061/clinics/2021/e3549', 'article-title': 'Effect of a single high-dose vitamin D3 on the length of hospital stay ' 'of severely 25-hydroxyvitamin D-deficient patients with COVID-19', 'volume': '76', 'author': 'Murai', 'year': '2021', 'journal-title': 'Clinics'}, { 'issue': '11', 'key': '10.1016/j.clnu.2023.09.008_bib37', 'doi-asserted-by': 'crossref', 'first-page': '1053', 'DOI': '10.1001/jama.2020.26848', 'article-title': 'Effect of a single high dose of vitamin D3 on hospital length of stay ' 'in patients with moderate to severe COVID-19: a randomized clinical ' 'trial', 'volume': '325', 'author': 'Murai', 'year': '2021', 'journal-title': 'JAMA'}, { 'issue': '10', 'key': '10.1016/j.clnu.2023.09.008_bib38', 'doi-asserted-by': 'crossref', 'first-page': '1358', 'DOI': '10.3390/medicina58101358', 'article-title': 'Evidence for the efficacy of a high dose of vitamin D on the ' 'hyperinflammation state in moderate-to-severe COVID-19 patients: a ' 'randomized clinical trial', 'volume': '58', 'author': 'Sarhan', 'year': '2022', 'journal-title': 'Medicina (Kaunas. Lithuania)'}, { 'key': '10.1016/j.clnu.2023.09.008_bib39', 'doi-asserted-by': 'crossref', 'DOI': '10.1177/20101058211041405', 'article-title': 'Impact of vitamin D therapy on the progress COVID-19: six weeks ' 'follow-up study of vitamin D deficient elderly diabetes patients', 'volume': '31', 'author': 'Soliman', 'year': '2022', 'journal-title': 'Proc Singapore Healthc'}, { 'issue': '2', 'key': '10.1016/j.clnu.2023.09.008_bib40', 'doi-asserted-by': 'crossref', 'first-page': 'e144', 'DOI': '10.7861/clinmed.2021-0035', 'article-title': 'Perspective: vitamin D supplementation prevents rickets and acute ' 'respiratory infections when given as daily maintenance but not as ' 'intermittent bolus: implications for COVID-19', 'volume': '21', 'author': 'Griffin', 'year': '2021', 'journal-title': 'Clin Med'}, { 'issue': '12', 'key': '10.1016/j.clnu.2023.09.008_bib41', 'doi-asserted-by': 'crossref', 'DOI': '10.1002/jbm4.10567', 'article-title': 'Vitamin D: bolus is bogus-A narrative review', 'volume': '5', 'author': 'Mazess', 'year': '2021', 'journal-title': 'JBMR plus'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib42', 'doi-asserted-by': 'crossref', 'first-page': '23380', 'DOI': '10.1038/s41598-021-02701-5', 'article-title': 'Real world evidence of calcifediol or vitamin D prescription and ' 'mortality rate of COVID-19 in a retrospective cohort of hospitalized ' 'Andalusian patients', 'volume': '11', 'author': 'Loucera', 'year': '2021', 'journal-title': 'Sci Rep'}, { 'issue': '8', 'key': '10.1016/j.clnu.2023.09.008_bib43', 'doi-asserted-by': 'crossref', 'first-page': '2358', 'DOI': '10.3390/nu12082358', 'article-title': 'Early nutritional interventions with zinc, selenium and vitamin D for ' 'raising anti-viral resistance against progressive COVID-19', 'volume': '12', 'author': 'Alexander', 'year': '2020', 'journal-title': 'Nutrients'}, { 'issue': '4', 'key': '10.1016/j.clnu.2023.09.008_bib44', 'doi-asserted-by': 'crossref', 'first-page': '568', 'DOI': '10.1093/infdis/jiaa713', 'article-title': 'Correlation between early plasma interleukin 37 responses with low ' 'inflammatory cytokine levels and benign clinical outcomes in severe ' 'acute respiratory syndrome coronavirus 2 infection', 'volume': '223', 'author': 'Li', 'year': '2021', 'journal-title': 'J\xa0Infect Dis'}, { 'key': '10.1016/j.clnu.2023.09.008_bib45', 'doi-asserted-by': 'crossref', 'first-page': '155702', 'DOI': '10.1016/j.cyto.2021.155702', 'article-title': 'Interleukin-37 is down-regulated in serum of patients with severe ' 'coronavirus disease 2019 (COVID-19)', 'volume': '148', 'author': 'Ahmed', 'year': '2021', 'journal-title': 'Cytokine'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib46', 'doi-asserted-by': 'crossref', 'first-page': '167', 'DOI': '10.1007/s40618-021-01639-9', 'article-title': 'Vitamin D supplementation and COVID-19 risk: a population-based, cohort ' 'study', 'volume': '45', 'author': 'Oristrell', 'year': '2022', 'journal-title': 'J\xa0Endocrinol Invest'}, { 'issue': '11', 'key': '10.1016/j.clnu.2023.09.008_bib47', 'doi-asserted-by': 'crossref', 'first-page': '1498', 'DOI': '10.1038/s41430-020-0558-y', 'article-title': 'Vitamin D deficiency 2.0: an update on the current status worldwide', 'volume': '74', 'author': 'Amrein', 'year': '2020', 'journal-title': 'Eur J Clin Nutr'}, { 'issue': '11', 'key': '10.1016/j.clnu.2023.09.008_bib48', 'doi-asserted-by': 'crossref', 'first-page': '1552', 'DOI': '10.7326/M21-3324', 'article-title': 'Vitamin D deficiency increases mortality risk in the UK biobank : a ' 'nonlinear mendelian randomization study', 'volume': '175', 'author': 'Sutherland', 'year': '2022', 'journal-title': 'Ann Intern Med'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib49', 'doi-asserted-by': 'crossref', 'first-page': '19397', 'DOI': '10.1038/s41598-022-24053-4', 'article-title': 'Association between vitamin D supplementation and COVID-19 infection ' 'and mortality', 'volume': '12', 'author': 'Gibbons', 'year': '2022', 'journal-title': 'Sci Rep'}, { 'key': '10.1016/j.clnu.2023.09.008_bib50', 'article-title': 'Prevention of covid-19 and other acute respiratory infections with cod ' 'liver oil supplementation, a low dose vitamin D supplement: quadruple ' 'blinded, randomised placebo controlled trial', 'volume': '378', 'author': 'Brunvoll', 'year': '2022', 'journal-title': 'Br Med J'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib51', 'doi-asserted-by': 'crossref', 'first-page': '130', 'DOI': '10.3390/ph16010130', 'article-title': 'Protective effect of vitamin D supplementation on COVID-19-related ' 'intensive care hospitalization and mortality: definitive evidence from ' 'meta-analysis and trial sequential analysis', 'volume': '16', 'author': 'Argano', 'year': '2023', 'journal-title': 'Pharmaceuticals'}, { 'issue': '2', 'key': '10.1016/j.clnu.2023.09.008_bib52', 'doi-asserted-by': 'crossref', 'first-page': '215', 'DOI': '10.1007/s13668-023-00471-2', 'article-title': 'A\xa0narrative review on the potential role of vitamin D(3) in the ' 'prevention, protection, and disease mitigation of acute and long ' 'COVID-19', 'volume': '12', 'author': 'Moukayed', 'year': '2023', 'journal-title': 'Current nutrition reports'}, { 'issue': '1', 'key': '10.1016/j.clnu.2023.09.008_bib53', 'first-page': '322', 'article-title': 'Role of vitamin-d supplementation in COVID-19 patients', 'volume': '2023', 'author': 'Salman', 'year': '2023'}, { 'issue': '4', 'key': '10.1016/j.clnu.2023.09.008_bib54', 'doi-asserted-by': 'crossref', 'first-page': '607', 'DOI': '10.1007/s00210-022-02360-x', 'article-title': 'Hospital and laboratory outcomes of patients with COVID-19 who received ' 'vitamin D supplementation: a systematic review and meta-analysis of ' 'randomized controlled trials', 'volume': '396', 'author': 'Zaazouee', 'year': '2023', 'journal-title': 'Naunyn-Schmiedeberg’s Arch Pharmacol'}], 'container-title': 'Clinical Nutrition', 'original-title': [], 'language': 'en', 'link': [ { 'URL': 'https://api.elsevier.com/content/article/PII:S0261561423002960?httpAccept=text/xml', 'content-type': 'text/xml', 'content-version': 'vor', 'intended-application': 'text-mining'}, { 'URL': 'https://api.elsevier.com/content/article/PII:S0261561423002960?httpAccept=text/plain', 'content-type': 'text/plain', 'content-version': 'vor', 'intended-application': 'text-mining'}], 'deposited': { 'date-parts': [[2023, 10, 6]], 'date-time': '2023-10-06T09:10:02Z', 'timestamp': 1696583402000}, 'score': 1, 'resource': {'primary': {'URL': 'https://linkinghub.elsevier.com/retrieve/pii/S0261561423002960'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2023, 11]]}, 'references-count': 54, 'journal-issue': {'issue': '11', 'published-print': {'date-parts': [[2023, 11]]}}, 'alternative-id': ['S0261561423002960'], 'URL': 'http://dx.doi.org/10.1016/j.clnu.2023.09.008', 'relation': {}, 'ISSN': ['0261-5614'], 'subject': ['Critical Care and Intensive Care Medicine', 'Nutrition and Dietetics'], 'container-title-short': 'Clinical Nutrition', 'published': {'date-parts': [[2023, 11]]}, 'assertion': [ {'value': 'Elsevier', 'name': 'publisher', 'label': 'This article is maintained by'}, { 'value': 'The role of vitamin D in the prevention and treatment of SARS-CoV-2 infection: ' 'A meta-analysis of randomized controlled trials', 'name': 'articletitle', 'label': 'Article Title'}, {'value': 'Clinical Nutrition', 'name': 'journaltitle', 'label': 'Journal Title'}, { 'value': 'https://doi.org/10.1016/j.clnu.2023.09.008', 'name': 'articlelink', 'label': 'CrossRef DOI link to publisher maintained version'}, {'value': 'article', 'name': 'content_type', 'label': 'Content Type'}, { 'value': '© 2023 The Author(s). Published by Elsevier Ltd.', 'name': 'copyright', 'label': 'Copyright'}]}