Micronutrient perspective on COVID-19: Umbrella review and reanalysis of meta-analyses
et al., Critical Reviews in Food Science and Nutrition, doi:10.1080/10408398.2023.2174948 (meta analysis), PROSPERO CRD42022353953
, Micronutrient perspective on COVID-19: Umbrella review and reanalysis of meta-analyses, Critical Reviews in Food Science and Nutrition, doi:10.1080/10408398.2023.2174948 (meta analysis), PROSPERO CRD42022353953
Systematic review and meta analysis of micronutrient supplementation, showing vitamin D supplementation associated with lower mortality, mechanical ventilation, ICU admission, and severity. Note that forest plots have OR>1 favoring supplementation. Vitamin D deficiency was also associated with higher mortality, mechanical ventilation, ICU admission, severity, and cases.Currently there are 111 vitamin D studies and meta analysis shows:
| Outcome | Improvement |
|---|---|
| Mortality | 37% lower [28‑44%] |
| Ventilation | 26% lower [-2‑46%] |
| ICU admission | 50% lower [33‑62%] |
| Hospitalization | 20% lower [8‑31%] |
| Cases | 16% fewer [7‑23%] |
This study includes zinc and vitamin D.
Xie et al., 15 Feb 2023, peer-reviewed, 16 authors, trial PROSPERO CRD42022353953.
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