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Vitamin D Status is Associated With In-hospital Mortality and Mechanical Ventilation: A Cohort of COVID-19 Hospitalized Patients

Angelidi et al., Mayo Clinic Proceedings, doi:10.1016/j.mayocp.2021.01.001
Jan 2021  
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Mortality 88% Improvement Relative Risk Vitamin D for COVID-19  Angelidi et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 144 patients in the USA Lower mortality with higher vitamin D levels (p=0.01) c19early.org Angelidi et al., Mayo Clinic Proceedings, Jan 2021 Favorsvitamin D Favorscontrol 0 0.5 1 1.5 2+
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 79 treatments. c19early.org
Retrospective 144 patients in the USA showing significantly lower mortality for vitamin D levels >=30ng/mL.
This is the 38th of 199 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 835,162 vigintillion).
risk of death, 88.0% lower, RR 0.12, p = 0.01, high D levels 6 of 65 (9.2%), low D levels 20 of 79 (25.3%), NNT 6.2, adjusted per study, >30ng/mL, supplementary table 2, multivariable logistic regression model 5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Angelidi et al., 9 Jan 2021, retrospective, USA, peer-reviewed, 8 authors.
This PaperVitamin DAll
Vitamin D Status Is Associated With In-Hospital Mortality and Mechanical Ventilation: A Cohort of COVID-19 Hospitalized Patients
MD Angeliki M Angelidi, PhD Matthew J Belanger, MD Michael K Lorinsky, MD Dimitrios Karamanis, PhD Natalia Chamorro-Pareja, MD Jennifer Ognibene, BA Leonidas Palaiodimos, MD, MSc Christos S Mantzoros
Mayo Clinic Proceedings, doi:10.1016/j.mayocp.2021.01.001
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
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