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0 0.5 1 1.5 2+ Mortality 33% Improvement Relative Risk c19early.org/s Mustafa et al. Remdesivir for COVID-19 LATE TREATMENT Is late treatment with remdesivir beneficial for COVID-19? Retrospective 444 patients in Pakistan Lower mortality with remdesivir (not stat. sig., p=0.21) Mustafa et al., Exploratory Research in Clinical.., doi:10.1016/j.rcsop.2021.100101 Favors remdesivir Favors control
Pattern of medication utilization in hospitalized patients with COVID-19 in three District Headquarters Hospitals in the Punjab province of Pakistan
Mustafa et al., Exploratory Research in Clinical and Social Pharmacy, doi:10.1016/j.rcsop.2021.100101
Mustafa et al., Pattern of medication utilization in hospitalized patients with COVID-19 in three District Headquarters.., Exploratory Research in Clinical and Social Pharmacy, doi:10.1016/j.rcsop.2021.100101
Dec 2021   Source   PDF  
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Retrospective 444 hospitalized patients in Pakistan, showing lower mortality with remdesivir treatment in unadjusted results, not reaching statistical significance.
[Gérard, Zhou] show significantly increased risk of acute kidney injury with remdesivir. This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
risk of death, 32.7% lower, RR 0.67, p = 0.21, treatment 16 of 200 (8.0%), control 29 of 244 (11.9%), NNT 26.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mustafa et al., 29 Dec 2021, retrospective, Pakistan, peer-reviewed, 7 authors.
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Abstract: Journal Pre-proof Pattern of medication utilization in hospitalized patients with COVID-19 in three District Headquarters Hospitals in the Punjab province of Pakistan Zia Ul Mustafa, Chia Siang Kow, Muhammad Salman, Mahpara Kanwal, Muhammad Bilal Riaz, Samina Parveen, Syed Shahzad Hasan PII: S2667-2766(21)00101-3 DOI: https://doi.org/10.1016/j.rcsop.2021.100101 Reference: RCSOP 100101 To appear in: Received date: 29 September 2021 Revised date: 15 December 2021 Accepted date: 27 December 2021 Please cite this article as: Z.U. Mustafa, C.S. Kow, M. Salman, et al., Pattern of medication utilization in hospitalized patients with COVID-19 in three District Headquarters Hospitals in the Punjab province of Pakistan, (2021), https://doi.org/10.1016/ j.rcsop.2021.100101 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2021 Published by Elsevier Inc. Journal Pre-proof Pattern of medication utilization in hospitalized patients with COVID-19 in three District Headquarters Hospitals in the Punjab province of Pakistan Zia Ul Mustafa1, Chia Siang Kow2,3, Muhammad Salman4, Mahpara Kanwal5, Muhammad Bilal Riaz6, Samina Parveen6, Syed Shahzad Hasan7,8 1 Department of Pharmacy Services, District Headquarter (DHQ) Hospital, Pakpattan 57400, Pakistan, Zia.ucp@gmail.com 2 School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia 3 School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia 4 Department of Pharmacy, The University of the Department of Pharmacy Services, District (DHQ) Hospital, Chakwal, Pr Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, United Kingdom School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, Australia Jo u rn al 8 Headquarter e- drbilalriaz@gmail.com & Rphsaminak@gmail.com 7 Pakistan, oo mahparakanwal89@gmail.com 6 54000 Department of Pharmacy Services, District Headquarter (DHQ) Hospital, Okara South City, Pakistan, pr 5 Lahore f msk5012@gmail.com Lahore, Abstract Journal Pre-proof Purpose In Pakistan, a wide range of repurposed drugs are recommended to manage hospitalized patients with COVID-19. Therefore, the current study was conducted to evaluate the pattern of utilization of repurposed drugs and other potential therapeutic options among hospitalized patients with COVID19 in Pakistan. Methods This retrospective, multicenter, descriptive study enrolled consecutive hospitalized patients with COVID-19 who were admitted between March 1, 2021, and April 30, 2021, from three District Headquarter Hospitals in the Punjab province of Pakistan. We describe patient and clinical characteristics and medications, stratified by COVID-19 severity during hospitalization: mild, moderate, and severe. In addition, an analytical study of drug utilization was conducted. oo f Findings Pr e- pr A total of 444 hospitalized patients with..
Late treatment
is less effective
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