Epidemiology, outcomes, and utilization of intensive care unit resources for critically ill COVID-19 patients in Libya: A prospective multi-center cohort study
Elhadi et al.,
Epidemiology, outcomes, and utilization of intensive care unit resources for critically ill COVID-19 patients..,
PLOS ONE, doi:10.1371/journal.pone.0251085
Prospective study of 465 COVID-19 ICU patients in Libya showing no significant differences with treatment.
[Gérard, Zhou] show significantly increased risk of acute kidney injury with remdesivir.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details.
risk of death, 10.9% higher, RR 1.11, p = 0.65, treatment 14 of 21 (66.7%), control 267 of 444 (60.1%).
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Elhadi et al., 30 Apr 2021, prospective, Libya, peer-reviewed, 21 authors, study period 29 May, 2020 - 30 December, 2020.
Abstract: PLOS ONE
RESEARCH ARTICLE
Epidemiology, outcomes, and utilization of
intensive care unit resources for critically ill
COVID-19 patients in Libya: A prospective
multi-center cohort study
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Muhammed Elhadi ID1*, Ahmed Alsoufi1, Abdurraouf Abusalama2, Akram Alkaseek3,
Saedah Abdeewi4, Mohammed Yahya5, Alsnosy Mohammed5, Mohammed Abdelkabir4,
Mohammed Huwaysh6, Emad Amkhatirah5, Kamel Alshorbaji7, Samer Khel8,
Marwa Gamra9, Abdulmueti Alhadi10,11, Taha Abubaker12, Mohamed Anaiba7,
Mohammed Elmugassabi7, Muhannud Binnawara13, Ala Khaled1, Ahmed Zaid1,
Ahmed Msherghi1
1 Faculty of Medicine University of Tripoli, Tripoli, Libya, 2 Almwasfat Isolation Hospital, Tripoli, Libya,
3 Gharyan Hospital, Gharyan, Libya, 4 Sebha Medical Center, Sebha, Libya, 5 Almarj Teaching Hospital,
Almarj, Libya, 6 Alshahid Attia Alkasah General Hospital, Alkufra, Libya, 7 Misurata Medical Center,
Misurata, Libya, 8 Soq Altholatha Isolation Center, Tripoli, Libya, 9 Emeitiga Military Hospital, Tripoli, Libya,
10 Sorman Isolation Center, Sorman, Libya, 11 Faculty of Medicine, University of Zawia, Az Zawiyah, Libya,
12 Benghazi Medical Center, Benghazi, Libya, 13 Tripoli Central Hospital, Tripoli, Libya
OPEN ACCESS
Citation: Elhadi M, Alsoufi A, Abusalama A,
Alkaseek A, Abdeewi S, Yahya M, et al. (2021)
Epidemiology, outcomes, and utilization of
intensive care unit resources for critically ill COVID19 patients in Libya: A prospective multi-center
cohort study. PLoS ONE 16(4): e0251085. https://
doi.org/10.1371/journal.pone.0251085
Editor: Aleksandar R. Zivkovic, Heidelberg
University Hospital, GERMANY
Received: March 11, 2021
Accepted: April 19, 2021
Published: April 30, 2021
Copyright: © 2021 Elhadi et al. This is an open
access article distributed under the terms of the
Creative Commons Attribution License, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the original
author and source are credited.
Data Availability Statement: All relevant data are
within the manuscript. The complete dataset is not
publicly available out of consideration for patient
confidentiality. Data contain potentially identifying
and sensitive patient information cannot be shared
publicly without permission from the hospitals
participating in the study. Because of the clinical
dataset’s granularity, it is impossible to adequately
anonymize it to avoid reidentification of participants
without jeopardizing study participants
confidentiality. If the requisite ethical approvals and
* Muhammed.elhadi.uot@gmail.com
Abstract
Background
The coronavirus disease (COVID-19) pandemic has severely affected African countries,
specifically the countries, such as Libya, that are in constant conflict. Clinical and laboratory
information, including mortality and associated risk factors in relation to hospital settings
and available resources, about critically ill patients with COVID-19 in Africa is not available.
This study aimed to determine the mortality and morbidity of COVID-19 patients in intensive
care units (ICU) following 60 days after ICU admission, and explore the factors that influence in-ICU mortality rate.
Methods
This is a multicenter prospective observational study among COVID-19 critical care patients
in 11 ICUs in Libya from May 29th to December 30th 2020. Basic demographic data, clinical
characteristics, laboratory values, admission Sequential Organ Failure Assessment (SOFA)
score, quick..
Late treatment
is less effective
elhadi
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